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生长抑素持续抑制家禽的生长激素分泌。

Somatostatin tonically inhibits growth hormone secretion in domestic fowl.

作者信息

Harvey S, Lam S K, Hall T R

出版信息

J Endocrinol. 1986 Oct;111(1):91-7. doi: 10.1677/joe.0.1110091.

DOI:10.1677/joe.0.1110091
PMID:2878057
Abstract

Passive immunization of immature chickens with sheep somatostatin (SRIF) antiserum promptly increased the basal plasma GH concentration and augmented TRH-induced GH secretion. Although exogenous SRIF had no inhibitory effect on the basal GH concentration in untreated birds or birds pretreated with non-immune sheep serum, it suppressed the stimulatory effect of SRIF immunoneutralization on GH secretion. These results suggest that SRIF is physiologically involved in the control of GH secretion in birds, in which it appears to inhibit GH release tonically.

摘要

用绵羊生长抑素(SRIF)抗血清对未成熟鸡进行被动免疫,可迅速提高基础血浆生长激素(GH)浓度,并增强促甲状腺激素释放激素(TRH)诱导的GH分泌。尽管外源性SRIF对未处理的鸡或用非免疫绵羊血清预处理的鸡的基础GH浓度没有抑制作用,但它抑制了SRIF免疫中和对GH分泌的刺激作用。这些结果表明,SRIF在鸟类GH分泌的调控中具有生理作用,在鸟类中它似乎持续抑制GH释放。

相似文献

1
Somatostatin tonically inhibits growth hormone secretion in domestic fowl.生长抑素持续抑制家禽的生长激素分泌。
J Endocrinol. 1986 Oct;111(1):91-7. doi: 10.1677/joe.0.1110091.
2
Somatostatin immunoneutralization overcomes the inhibitory effects of quipazine and pargyline on growth hormone secretion in domestic fowl.生长抑素免疫中和可克服喹哌嗪和优降宁对家禽生长激素分泌的抑制作用。
Experientia. 1987 Jun 15;43(6):602-4. doi: 10.1007/BF02126345.
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Somatostatin inhibition of growth hormone secretion in an adult bird: the domestic fowl.生长抑素对成年鸟类(家鸡)生长激素分泌的抑制作用
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Somatostatin-28(1-14) immunoneutralization stimulates growth hormone secretion in fowl.生长抑素-28(1-14)免疫中和作用刺激家禽生长激素分泌。
Gen Comp Endocrinol. 1987 Jan;65(1):111-6. doi: 10.1016/0016-6480(87)90229-2.
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Physiological control of growth hormone secretion by thyrotrophin-releasing hormone in the domestic fowl.
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Inhibition of growth hormone secretion in anaesthetized fowl: hypothalamic participation.麻醉禽类生长激素分泌的抑制:下丘脑的作用
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The effect of thyrotropin-releasing hormone (TRH) and somatostatin (GHRIH) on growth hormone and prolactin secretion in vitro and in vivo in the domestic fowl (Gallus domesticus).促甲状腺激素释放激素(TRH)和生长抑素(GHRIH)对家鸡(原鸡)体内外生长激素和催乳素分泌的影响。
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Acute or chronic immunoneutralization of somatostatin does not affect growth hormone or thyroid hormone secretion in sheep.
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引用本文的文献

1
Synthetic growth hormone secretagogues control growth hormone secretion in the chicken at pituitary and hypothalamic levels.合成生长激素促分泌素在垂体和下丘脑水平控制鸡的生长激素分泌。
Endocrine. 2001 Feb;14(1):67-72. doi: 10.1385/ENDO:14:1:067.
2
Somatostatin immunoneutralization overcomes the inhibitory effects of quipazine and pargyline on growth hormone secretion in domestic fowl.生长抑素免疫中和可克服喹哌嗪和优降宁对家禽生长激素分泌的抑制作用。
Experientia. 1987 Jun 15;43(6):602-4. doi: 10.1007/BF02126345.