Harvey S, Lam S K, Hall T R
J Endocrinol. 1986 Oct;111(1):91-7. doi: 10.1677/joe.0.1110091.
Passive immunization of immature chickens with sheep somatostatin (SRIF) antiserum promptly increased the basal plasma GH concentration and augmented TRH-induced GH secretion. Although exogenous SRIF had no inhibitory effect on the basal GH concentration in untreated birds or birds pretreated with non-immune sheep serum, it suppressed the stimulatory effect of SRIF immunoneutralization on GH secretion. These results suggest that SRIF is physiologically involved in the control of GH secretion in birds, in which it appears to inhibit GH release tonically.
用绵羊生长抑素(SRIF)抗血清对未成熟鸡进行被动免疫,可迅速提高基础血浆生长激素(GH)浓度,并增强促甲状腺激素释放激素(TRH)诱导的GH分泌。尽管外源性SRIF对未处理的鸡或用非免疫绵羊血清预处理的鸡的基础GH浓度没有抑制作用,但它抑制了SRIF免疫中和对GH分泌的刺激作用。这些结果表明,SRIF在鸟类GH分泌的调控中具有生理作用,在鸟类中它似乎持续抑制GH释放。