Cheng Chi-Wai, Chan Lung-Wai, Ng Chi-Fai, Chan Chi-Kwok, Tse Man-Kit Gary, Lai Mac-Moune Fernand
Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.
Int J Urol. 2006 Apr;13(4):463-5. doi: 10.1111/j.1442-2042.2006.01327.x.
A case of prostate cancer metastasized to the breast is presented, the latter being prostate-specific antigen (PSA) positive. This is the first of such cases reported in Hong Kong and China in the English literature. As PSA expression also can be found in primary breast cancer, prostatic acid phosphatase staining was employed to confirm the diagnosis. The relationship of PSA and non-prostatic tissues is reviewed. The differential diagnosis of breast enlargement in patients known to have prostate malignancy also is discussed.
本文报告了一例前列腺癌转移至乳腺的病例，该乳腺组织前列腺特异性抗原（PSA）呈阳性。这是英文文献中首次报道的在香港和中国出现的此类病例。由于原发性乳腺癌中也可发现PSA表达，因此采用前列腺酸性磷酸酶染色来确诊。本文还回顾了PSA与非前列腺组织的关系。同时也讨论了已知患有前列腺恶性肿瘤的患者乳腺增大的鉴别诊断。
