Yokoyama Shohei, Fukuhara Shinichiro, Imazu Tetsuo, Hara Tsuneo, Yamaguchi Seiji, Adachi Shiro
Department of Urology, Ikeda municipal Hospital.
Hinyokika Kiyo. 2007 Jul;53(7):485-7.
We report a case of primary adenocarcinoma of the prostate producing carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9). A 64-year-old man referred to our hospital with dysbasia. Two years ago, he was diagnosed with prostate cancer at another hospital and received radiotherapy and endocrine therapy. Serum CEA and CA 19-9 levels were increased to 3,990 ng/ml and 11,700 U/ml at the time of our hospitalization. However, his serum PSA level remained low. After hospitalization, the disease rapidly progressed and he died a month later. In the histology of autopsy specimen, the prostate showed no sign of malignancy, but bone showed metastasis of prostate cancer. Immunohistochemical staining for CEA and PSA demonstrated the existence of each protein in bone metastasis.
我们报告一例产生癌胚抗原（CEA）和糖类抗原19-9（CA19-9）的前列腺原发性腺癌病例。一名64岁男性因排尿困难转诊至我院。两年前，他在另一家医院被诊断为前列腺癌，并接受了放疗和内分泌治疗。我院住院时血清CEA和CA 19-9水平分别升至3990 ng/ml和11700 U/ml。然而，他的血清PSA水平仍然很低。住院后，病情迅速进展，一个月后死亡。尸检标本的组织学检查显示前列腺无恶性迹象，但骨骼有前列腺癌转移。对骨转移灶进行CEA和PSA免疫组化染色显示各蛋白均存在。
