van Wijk I, Lindeman E, Kappelle L J, van Gijn J, Koudstaal P J, Gorter J W, Algra A
Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands.
J Neurol Neurosurg Psychiatry. 2006 Nov;77(11):1238-43. doi: 10.1136/jnnp.2006.089391. Epub 2006 May 30.
Stroke may have a major effect on survivors and on the healthcare system.
To study the functional status and use of healthcare facilities in long-term survivors of a transient ischaemic attack (TIA) or minor ischaemic stroke (MIS) and evaluate associations with baseline and follow-up characteristics.
Follow-up of patients who had participated in the Dutch TIA Trial or the European Atrial Fibrillation Trial was extended to a mean period of 15.6 years. Patients were interviewed through a postal questionnaire (n = 468) and a sample of this group was also interviewed at home (n = 198). Demographic data, information on comorbidity, functional status (Barthel Index, Frenchay Activities Index and modified Rankin Scale) and use of healthcare facilities were recorded.
About one third of the survivors interviewed at home experienced any residual disability and 26% were moderately to severely handicapped. Factors associated with poor functional status were advanced age and the presence of any infarct on a baseline computed tomography scan, the recurrence of a new major stroke or the presence of comorbidity of locomotion. One third of survivors used any kind of professional care, which was predominantly related to the functional status at follow-up.
Recurrent stroke and the presence of comorbidity of locomotion are important determinants of long-term disability of survivors of a TIA or an MIS, which, in turn, is strongly associated with the long-term use of professional care. The need for measuring comorbidity with regard to functional status is recommended in research on stroke outcome.
中风可能对幸存者及医疗保健系统产生重大影响。
研究短暂性脑缺血发作(TIA)或轻度缺血性中风(MIS)长期幸存者的功能状态及医疗保健设施的使用情况,并评估其与基线及随访特征的关联。
对参与荷兰TIA试验或欧洲心房颤动试验的患者进行随访,随访期平均延长至15.6年。通过邮寄问卷对患者进行访谈(n = 468),并对该组中的一个样本进行家访(n = 198)。记录人口统计学数据、合并症信息、功能状态(Barthel指数、Frenchay活动指数和改良Rankin量表)以及医疗保健设施的使用情况。
在家访的幸存者中,约三分之一有任何残留残疾,26%为中度至重度残疾。与功能状态不佳相关的因素包括高龄、基线计算机断层扫描显示有任何梗死灶、新发重大中风复发或存在运动合并症。三分之一的幸存者使用了任何形式的专业护理,这主要与随访时的功能状态有关。
复发性中风和运动合并症的存在是TIA或MIS幸存者长期残疾的重要决定因素,而这又与长期使用专业护理密切相关。建议在中风结局研究中测量与功能状态相关的合并症。