van Wijk I, Gorter J W, Lindeman E, Kappelle L J, van Gijn J, Koudstaal P J, Algra A
Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands.
J Neurol. 2007 Aug;254(8):1018-25. doi: 10.1007/s00415-006-0480-9. Epub 2007 Mar 25.
Stroke has a major impact on survivors. Our study was designed to describe the mental status and health-related quality of life (HRQoL) in long-term survivors of TIA or minor ischaemic stroke (MIS) and evaluate associations of mental and physical factors with HR-QoL.
A random sample of the 10-year survivors of the Dutch TIA Trial (DTT) and the dutch participants of the European Atrial Fibrillation Trial (EAFT) were interviewed by postal questionnaire (n = 468) and at home (n = 198). Demographic data, mental health status (depression (CES-D), cognition (CAMCOG)), and health perception (SF-36 and Euroqol) were measured.
198 long-term survivors were included; mean age was 72.5 (SD 8.7 years), 22% was depressed (CES-D > or = 16) and 15% had cognitive dysfunction (CAMCOG < 80). The overall HR-QoL did not differ much from the norm population. Physical disability, occurrence of a major stroke and comorbidity of locomotion or the heart were independently associated with a low health perception.
Despite varying amounts of disability, the majority of long-term survivors of a TIA or MIS rated their quality of life as rather good. Physical factors, rather than mental status were independently related to a decrease in perceived health.
中风对幸存者有重大影响。我们的研究旨在描述短暂性脑缺血发作(TIA)或轻度缺血性中风(MIS)长期幸存者的心理状态和健康相关生活质量(HRQoL),并评估心理和身体因素与健康相关生活质量的关联。
通过邮寄问卷(n = 468)和上门访谈(n = 198)的方式,对荷兰TIA试验(DTT)的10年幸存者和欧洲心房颤动试验(EAFT)的荷兰参与者进行随机抽样调查。测量人口统计学数据、心理健康状况(抑郁(CES-D)、认知(CAMCOG))和健康认知(SF-36和Euroqol)。
纳入198名长期幸存者;平均年龄为72.5岁(标准差8.7岁),22%有抑郁(CES-D≥16),15%有认知功能障碍(CAMCOG<80)。总体健康相关生活质量与正常人群差异不大。身体残疾、发生重大中风以及运动或心脏合并症与健康认知度低独立相关。
尽管残疾程度各不相同,但大多数TIA或MIS长期幸存者对其生活质量的评价相当不错。身体因素而非心理状态与感知健康下降独立相关。