Lefflerová K, Widimský J, Lupínek Z
Katedra kardiologie ILF, Praha.
Vnitr Lek. 1991 Feb;37(2):128-34.
The authors investigated the effectiveness of treatment of hypertension by monotherapy with beta-blockers--bopindolol (a beta-blocker with a slightly expressed ISA) and metoprolol (cardioselective beta-blocker) in 86 subjects with mild and medium severe hypertension. The purpose of the work was to analyze the effectiveness of control of hypertension in relation to age and to compare groups of subjects under 40 years with patients above 60 years of age. Both investigated beta-blockers proved effective in 80% of subjects above 60 years in the control of hypertension; no serious side-effects were recorded.
作者研究了β受体阻滞剂(波吲洛尔,一种具有轻微内在拟交感活性的β受体阻滞剂;美托洛尔,心脏选择性β受体阻滞剂)单药治疗86例轻、中度高血压患者的疗效。该研究的目的是分析高血压控制效果与年龄的关系,并比较40岁以下和60岁以上的受试者组。在60岁以上的受试者中,两种被研究的β受体阻滞剂在控制高血压方面均有80%的有效性;未记录到严重副作用。