Maleki Norouz, Safavi Afsaneh, Tajabadi Fariba
Department of Chemistry, College of Sciences, Shiraz University, Shiraz, 71454, Iran.
Anal Chem. 2006 Jun 1;78(11):3820-6. doi: 10.1021/ac060070+.
Ionic liquid, n-octylpyridinum hexafluorophosphate (OPFP) has been used to fabricate a new carbon composite electrode with very attractive electrochemical behavior. This type of carbon electrode has been constructed using graphite mixed with OPFP as the binder. The electrode has combined advantages of edge plane characteristics of carbon nanotubes and edge plane pyrolytic graphite electrodes together with the low cost of carbon paste electrodes and robustness of metallic electrodes. It provides a remarkable increase in the rate of electron transfer of different organic and inorganic electroactive compounds and offers a marked decrease in the overvoltage for biomolecules such as NADH, dopamine, and ascorbic acid. It also circumvents NADH surface fouling effects as well as furnishing higher current density for a wide range of compounds tested. Depending on the choice of the electrolyte, the electrode can have the ion-exchange property and adsorptive characteristics of clay-modified electrodes. The proposed electrode thus allows sensitive, low-potential, simple, low-cost, and stable electrochemical sensing of biomolecules and other electroactive compounds. Scanning electron microscopy images indicate significant improvement in the microstructure of the proposed electrode compared to carbon paste electrodes. Such abilities promote new opportunities for a wide range of electrochemical and biosensing applications.
离子液体正辛基吡啶六氟磷酸盐（OPFP）已被用于制备一种具有极具吸引力的电化学行为的新型碳复合电极。这种类型的碳电极是通过将石墨与OPFP混合作为粘合剂构建而成的。该电极兼具碳纳米管边缘平面特性和边缘平面热解石墨电极的优点，同时具备碳糊电极的低成本以及金属电极的坚固性。它显著提高了不同有机和无机电活性化合物的电子转移速率，并显著降低了生物分子（如NADH、多巴胺和抗坏血酸）的过电压。它还能避免NADH表面污染效应，并且为所测试的广泛化合物提供更高的电流密度。根据电解质的选择，该电极可以具有粘土改性电极的离子交换特性和吸附特性。因此，所提出的电极能够对生物分子和其他电活性化合物进行灵敏、低电位、简单、低成本且稳定的电化学传感。扫描电子显微镜图像表明，与碳糊电极相比，所提出电极的微观结构有显著改善。这些特性为广泛的电化学和生物传感应用带来了新机遇。
