小儿原位肝移植术后巨细胞病毒相关噬血细胞综合征的成功治疗
Successful treatment of cytomegalovirus-associated haemophagocytic syndrome following paediatric orthotopic liver transplantation.
作者信息
Hardikar Winita, Pang Ken, Al-Hebbi Homoud, Curtis Nigel, Couper Richard
机构信息
Department of Gastroenterology, University of Melbourne, Royal Children's Hospital, Melbourne, Victoria, Australia.
出版信息
J Paediatr Child Health. 2006 Jun;42(6):389-91. doi: 10.1111/j.1440-1754.2006.00879.x.
Haemophagocytic syndrome (HPS) following orthotopic liver transplantation is a rare event which is often fatal. We report here a case of HPS in association with cytomegalovirus (CMV) reactivation. The patient was treated with a combination of antiviral agents, immunomodulatory and supportive therapy which resulted in suppression of CMV infection and resolution of the haemophagocytosis.
原位肝移植后发生噬血细胞综合征（HPS）是一种罕见事件，通常是致命的。我们在此报告一例与巨细胞病毒（CMV）再激活相关的HPS病例。该患者接受了抗病毒药物、免疫调节和支持治疗的联合治疗，结果CMV感染得到抑制，噬血细胞现象消退。
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