Singh Jasvinder A, Solomon Daniel H, Dougados Maxime, Felson David, Hawker Gillian, Katz Patricia, Paulus Hal, Wallace Carol
Arthritis Rheum. 2006 Jun 15;55(3):348-52. doi: 10.1002/art.22003.
Clinicians already know that not all patients who are diagnosed with rheumatic diseases really have them. Moreover, determining which patients have improved and by how much is also difficult. Classification criteria allow clinical researchers to recruit patients with similar diseases (e.g., rheumatoid arthritis or systemic lupus erythematosus) into studies. Response criteria help to determine whether treatments really work, i.e., whether they actually produce clinically important improvement. As the science of clinical research advances, we must update our standards for considering classification and response criteria. In this editorial, members of the American College of Rheumatology (ACR) Subcommittee on Classification and Response Criteria describe the purpose of criteria sets, their development and validation, and the role of the ACR in adopting them.
临床医生已经知道，并非所有被诊断患有风湿性疾病的患者都真的患有这些疾病。此外，确定哪些患者病情有所改善以及改善程度如何也很困难。分类标准使临床研究人员能够招募患有相似疾病（如类风湿关节炎或系统性红斑狼疮）的患者进行研究。反应标准有助于确定治疗方法是否真的有效，即它们是否真的能产生具有临床意义的改善。随着临床研究科学的进步，我们必须更新我们考虑分类和反应标准的标准。在这篇社论中，美国风湿病学会（ACR）分类和反应标准小组委员会的成员描述了标准集的目的、其制定和验证过程，以及ACR在采用这些标准方面的作用。
