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急诊科社区获得性肺炎的治疗方法及氟喹诺酮类药物的适当作用。

Approaches to treatment of community-acquired pneumonia in the emergency department and the appropriate role of fluoroquinolones.

作者信息

Moran Gregory

机构信息

Department of Emergency Medicine and Division of Infectious Diseases, UCLA Medical Center, Sylmar, California 91342, USA.

出版信息

J Emerg Med. 2006 May;30(4):377-87. doi: 10.1016/j.jemermed.2005.07.009.

Abstract

The Emergency Department is a critical point of care for patients presenting with signs and symptoms of community-acquired pneumonia (CAP). The initial diagnosis, the decision to admit or discharge, the timing of initiating treatment, and appropriateness of the empirical therapy are key factors in successful management. Rising resistance rates to commonly used CAP antibiotics has complicated empirical treatment. Respiratory fluoroquinolones represent an important therapeutic option for patients with co-morbidities and risk factors for penicillin-, macrolide-, and multi-drug-resistant S. pneumoniae infections. Ensuring appropriate use is required to maintain their high level of effectiveness in key respiratory pathogens. Treatment guidelines from the Infectious Diseases Society of America, American Thoracic Society, and Centers for Disease Control and Prevention are available to assist emergency physicians in developing clinical pathways to ensure appropriate use of available therapies.

摘要

急诊科是对出现社区获得性肺炎(CAP)体征和症状的患者进行关键治疗的场所。初始诊断、入院或出院的决定、开始治疗的时机以及经验性治疗的合理性是成功治疗的关键因素。常用CAP抗生素耐药率的上升使经验性治疗变得复杂。呼吸喹诺酮类药物是合并症患者以及有青霉素、大环内酯类和多重耐药肺炎链球菌感染风险因素患者的重要治疗选择。需要确保合理使用以维持其对关键呼吸道病原体的高效性。美国传染病学会、美国胸科学会和疾病控制与预防中心发布的治疗指南可帮助急诊医生制定临床路径,以确保合理使用现有疗法。

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