Khan Nadeem U, Razzak Junaid A
Section of Emergency Medicine, Department of Medicine, The Aga Khan University, Karachi, Pakistan.
J Emerg Med. 2006 May;30(4):411-3. doi: 10.1016/j.jemermed.2005.07.013.
We report a case of abdominal pain with rigidity, mimicking an acute abdomen, caused by metoclopramide, a common anti-emetic drug. Extrapyramidal symptoms are commonly reported side-effects of this medication. They generally include involuntary movements of limbs, torticollis, oculogyric crisis, rhythmic protrusion of tongue, trismus, or dystonic reactions resembling tetanus, etc. Abdominal rigidity due to this medication, resembling an acute abdomen, has not been reported previously. This case report illustrates the importance of considering medication side-effects when evaluating a patient with abdominal pain and rigidity.
我们报告一例由常见止吐药物甲氧氯普胺引起的腹痛伴腹肌紧张,类似急腹症的病例。锥体外系症状是该药物常见的副作用。它们通常包括肢体不自主运动、斜颈、动眼危象、舌头节律性伸出、牙关紧闭或类似破伤风的肌张力障碍反应等。此前尚未有因该药物导致类似急腹症的腹肌紧张的报道。本病例报告说明了在评估腹痛伴腹肌紧张的患者时考虑药物副作用的重要性。