Shear Katherine, Jin Robert, Ruscio Ayelet Meron, Walters Ellen E, Kessler Ronald C
Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA.
Am J Psychiatry. 2006 Jun;163(6):1074-83. doi: 10.1176/ajp.2006.163.6.1074.
Despite its inclusion in DSM-IV, little is known about the prevalence or correlates of adult separation anxiety disorder or its relationship to the childhood disorder. Results of the first epidemiological study of adult separation anxiety disorder, to the authors' knowledge, and its relationship to childhood separation anxiety disorder are presented.
Data were from the National Comorbidity Survey Replication (NCS-R), a nationally representative survey of U.S. households. A fully structured, lay-administered diagnostic interview assessed a wide range of DSM-IV disorders, including separation anxiety disorder. No independent clinical validation was obtained of the assessment.
Lifetime prevalence estimates of childhood and adult separation anxiety disorders were 4.1% and 6.6%, respectively. Approximately one-third of the respondents who were classified as childhood cases (36.1%) had an illness that persisted into adulthood, although the majority classified as adult cases (77.5%) had first onset in adulthood. The assessment of separation anxiety disorder in the NCS-R was comorbid with other NCS-R or DSM-IV disorders and associated with severe role impairment in roughly half of the comorbid cases and one-fourth of the pure cases. The majority of people with estimated adult separation anxiety disorder are untreated, even though many obtain treatment for comorbid conditions.
Criteria for adult separation anxiety disorder should be refined in future editions of DSM because the disorder is likely to be much more common in adults than previously recognized. Research is needed to develop and evaluate treatments that take into consideration its high comorbidity with other DSM-IV disorders.
尽管成人分离焦虑症已被纳入《精神疾病诊断与统计手册第四版》(DSM-IV),但对于其患病率、相关因素或与儿童期该疾病的关系,人们知之甚少。本文呈现了据作者所知的关于成人分离焦虑症的首次流行病学研究结果及其与儿童期分离焦虑症的关系。
数据来自全国共病调查复制研究(NCS-R),这是一项对美国家庭具有全国代表性的调查。通过一个完全结构化、由外行人实施的诊断访谈评估了包括分离焦虑症在内的多种DSM-IV疾病。该评估未获得独立的临床验证。
儿童期和成人分离焦虑症的终生患病率估计分别为4.1%和6.6%。约三分之一被归类为儿童期病例的受访者(36.1%)疾病持续到了成年期,尽管大多数被归类为成人期病例的受访者(77.5%)在成年期首次发病。NCS-R中对分离焦虑症的评估与其他NCS-R或DSM-IV疾病共病,并且在大约一半的共病病例和四分之一的单纯病例中与严重的角色功能损害相关。大多数估计患有成人分离焦虑症的人未接受治疗,尽管许多人因共病情况而接受治疗。
成人分离焦虑症的诊断标准应在DSM的未来版本中加以完善,因为该疾病在成年人中可能比之前认为的更为常见。需要开展研究以开发和评估考虑到其与其他DSM-IV疾病高共病性的治疗方法。