Barnas C, Fleischhacker W W, Whitworth A B, Schett P, Stuppäck C, Hinterhuber H
Department of Psychiatry, Innsbruck University Clinics, Austria.
Psychopharmacology (Berl). 1991;103(2):233-9. doi: 10.1007/BF02244209.
A sample of 171 benzodiazepine (bzd) users was investigated in the pharmacy where the patients filled in their prescriptions. Of the sample, 29.8% were males and 70.2% were females. About 60% of the patients had their current prescription from a general practitioner, the rest from different specialists. 70.8% stated to take bzds on more than 3 days of the week. The mean duration of intake of the entire sample was 4.5 years. The most frequent reasons for bzd intake were sleep disturbance followed by nervousness and somatic diseases. A total of 74.9% of the patients turned out to be well informed about the potential dependence hazards of bzd long term intake, but less than half of them had been informed by the prescribing physician. In a second step it could be demonstrated by means of multiple stepwise logistic regression analysis that certain characteristic parameters differentiate long-term users and persons with signs of potential abuse and dependence from other bzd users.
在患者取药的药房对171名苯二氮䓬（BZD）使用者进行了调查。在该样本中，男性占29.8%，女性占70.2%。约60%的患者目前的处方来自全科医生，其余来自不同专科医生。70.8%的患者表示每周服用BZD超过3天。整个样本的平均服用时长为4.5年。服用BZD最常见的原因是睡眠障碍，其次是紧张和躯体疾病。共有74.9%的患者对BZD长期服用的潜在成瘾风险有充分了解，但其中不到一半是由开处方的医生告知的。在第二步中，通过多步逐步逻辑回归分析可以证明，某些特征参数能够区分长期使用者以及有潜在滥用和成瘾迹象的人与其他BZD使用者。
