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大都市人群中精神药物的使用模式。

Psychotropic drug utilization patterns in a metropolitan population.

作者信息

Koenig W, Rüther E, Filipiak B

出版信息

Eur J Clin Pharmacol. 1987;32(1):43-51. doi: 10.1007/BF00609956.

Abstract

Psychotropic drug intake by a random sample of citizens of the city of Munich aged 30-69 years has been assessed. A 1-week prevalence of 9.3% for all psychotropic drug users was found, benzodiazepines accounting for approximately two-thirds (6.6%) of the users. Two-thirds of drug users were women. Drug use in both sexes increased with age. The doses of benzodiazepines prescribed in most cases were less than 10 mg diazepam equivalent per day. Intake of benzodiazepines in combination with analgesics or alcohol (greater than or equal to 40 g/day) did not appear to represent a major problem. Multiple logistic regression analysis showed that the number of chronic diseases was the strongest predictor of benzodiazepine intake in men, whereas stress and age determined intake in women. Long-term use seemed to be relatively rare at 11% of all benzodiazepine users, so it was not considered to be a severe public health problem.

摘要

对慕尼黑市30至69岁的随机抽样市民的精神药物摄入情况进行了评估。发现所有精神药物使用者的1周患病率为9.3%,其中苯二氮䓬类药物使用者约占三分之二(6.6%)。三分之二的药物使用者为女性。男女的药物使用都随年龄增长而增加。大多数情况下开具的苯二氮䓬类药物剂量低于每天10毫克地西泮当量。同时服用苯二氮䓬类药物与镇痛药或酒精(每天大于或等于40克)似乎不是一个主要问题。多元逻辑回归分析表明,慢性病数量是男性服用苯二氮䓬类药物的最强预测因素,而压力和年龄则决定了女性的药物摄入情况。长期使用者似乎相对较少,占所有苯二氮䓬类药物使用者的11%,因此不被视为严重的公共卫生问题。

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