Department of Biochemistry, Agricultural Research Council Institute of Animal Physiology Babraham, Cambridge CB2 4AT, U.K.
Biochem J. 1973 Jun;134(2):659-62. doi: 10.1042/bj1340659.
From ;pulse'-labelling experiments of Entodinium caudatum with [(14)C]ethanolamine and by incubating the organism with [(32)P]phosphatidylethanolamine it is concluded that phosphatidylethanolamine can act as a direct precursor of the phosphorylethanolamine moiety of ceramide phosphorylethanolamine. The phosphorylethanolamine is probably never liberated in the free form but is transferred directly to a ceramide or ceramide-containing acceptor. The results are also in agreement with previous conclusions that phosphatidylethanolamine is the direct lipid precursor of N-(1-carboxyethyl)phosphatidylethanolamine.
从用 [(14)C]乙醇胺对 Entodinium caudatum 进行的脉冲标记实验和用 [(32)P]磷脂酰乙醇胺孵育该生物体的结果可以得出结论，磷脂酰乙醇胺可以作为神经酰胺磷酸乙醇胺部分的直接前体。磷酸乙醇胺可能从未以游离形式释放，而是直接转移到神经酰胺或含神经酰胺的受体上。这些结果也与以前的结论一致，即磷脂酰乙醇胺是 N-(1-羧乙基)磷脂酰乙醇胺的直接脂质前体。
