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采用标准化纸片扩散法对厌氧菌进行药敏试验,特别针对脆弱拟杆菌。

Antibiotic susceptibility testing of anaerobic bacteria by the standardized disc diffusion method with special reference to bacteroides fragilis.

作者信息

Dornbusch K, Nord C E, Olsson B

出版信息

Scand J Infect Dis. 1975;7(1):59-66. doi: 10.3109/inf.1975.7.issue-1.11.

DOI:10.3109/inf.1975.7.issue-1.11
PMID:167431
Abstract

The susceptibility of 90 strains of Bacteroides fragilis to 16 antibacterial drugs was determined by the agar plate dilution test and the disc diffusion test. Good correlation of results was obtained with the two methods, and regression line analysis could be performed for beta-lactam antibiotics, erythromycin, tetracyclines, lincomycin and clindamycin. Thus the standardized disc diffusion method can be used for susceptibility testing, but only a clear distinction between sensitive and resistant strains can be seen.

摘要

采用琼脂平板稀释法和纸片扩散法测定了90株脆弱拟杆菌对16种抗菌药物的敏感性。两种方法的结果具有良好的相关性,并且可以对β-内酰胺类抗生素、红霉素、四环素、林可霉素和克林霉素进行回归线分析。因此,标准化纸片扩散法可用于药敏试验,但只能明确区分敏感菌株和耐药菌株。

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1
Antibiotic susceptibility testing of anaerobic bacteria by the standardized disc diffusion method with special reference to bacteroides fragilis.采用标准化纸片扩散法对厌氧菌进行药敏试验,特别针对脆弱拟杆菌。
Scand J Infect Dis. 1975;7(1):59-66. doi: 10.3109/inf.1975.7.issue-1.11.
2
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引用本文的文献

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Practical anaerobic broth-disk elution susceptibility test.实用厌氧肉汤-纸片洗脱药敏试验
Antimicrob Agents Chemother. 1980 Apr;17(4):740-2. doi: 10.1128/AAC.17.4.740.
2
Liquid chromatographic assay for metronidazole and tinidazole: pharmacokinetic and metabolic studies in human subjects.甲硝唑和替硝唑的液相色谱测定法:人体药代动力学和代谢研究
Antimicrob Agents Chemother. 1981 May;19(5):754-60. doi: 10.1128/AAC.19.5.754.
3
Introduction of anaerobic methodology into a clinical microbiological laboratory.将厌氧培养方法引入临床微生物学实验室。
Infection. 1980;8 Suppl 2:S163-6. doi: 10.1007/BF01639884.
4
Properties of a new penicillinase type produced by Bacteroides fragilis.脆弱拟杆菌产生的一种新型青霉素酶的特性
Antimicrob Agents Chemother. 1982 Oct;22(4):579-84. doi: 10.1128/AAC.22.4.579.
5
Studies on beta-lactamase in Bacteroides fragilis.脆弱拟杆菌中β-内酰胺酶的研究。
Infection. 1980;8 Suppl 2:S167-70. doi: 10.1007/BF01639885.
6
Characterization of three different beta-lactamases from the Bacteroides fragilis group.脆弱拟杆菌群中三种不同β-内酰胺酶的特性分析。
Antimicrob Agents Chemother. 1980 Aug;18(2):220-5. doi: 10.1128/AAC.18.2.220.
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Tinidazole in anaerobic infections: a review of its antibacterial activity, pharmacological properties and therapeutic efficacy.替硝唑在厌氧菌感染中的应用:抗菌活性、药理特性及治疗效果综述
Drugs. 1982 Aug;24(2):85-117. doi: 10.2165/00003495-198224020-00001.
8
Methods for testing antibiotic sensitivity of anaerobic bacteria.
Infection. 1980;8 Suppl 2:S171-5. doi: 10.1007/BF01639886.
9
Cephamycin inactivation due to enzymatic hydrolysis by beta-lactamase from Bacteroides fragilis.脆弱拟杆菌产生的β-内酰胺酶通过酶促水解导致头孢霉素失活。
Antimicrob Agents Chemother. 1985 Dec;28(6):773-7. doi: 10.1128/AAC.28.6.773.
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Comparative growth rates of selected anaerobic species in four commonly used broth media.四种常用肉汤培养基中特定厌氧菌的比较生长速率。
Antimicrob Agents Chemother. 1977 Mar;11(3):482-90. doi: 10.1128/AAC.11.3.482.