Studies in the biochemistry of micro-organisms: The formation from glucose by members of the Penicillium chrysogenum series of a pigment, an alkali-soluble protein and penicillin-the antibacterial substance of Fleming.
作者信息
Clutterbuck P W, Lovell R, Raistrick H
机构信息
The Divisions of Biochemistry and Bacteriology, London School of Hygiene and Tropical Medicine, University of London.
出版信息
Biochem J. 1932;26(6):1907-18. doi: 10.1042/bj0261907.
Abstract
摘要
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Studies in the biochemistry of micro-organisms: The formation from glucose by members of the Penicillium chrysogenum series of a pigment, an alkali-soluble protein and penicillin-the antibacterial substance of Fleming.微生物生物化学研究：产黄青霉属系列成员由葡萄糖形成一种色素、一种碱溶性蛋白质和青霉素——弗莱明的抗菌物质。
Biochem J. 1932;26(6):1907-18. doi: 10.1042/bj0261907.
2
Why did the Fleming strain fail in penicillin industry?弗莱明菌株为何在青霉素工业中失败了？
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Transcriptional and bioinformatic analysis of the 56.8 kb DNA region amplified in tandem repeats containing the penicillin gene cluster in Penicillium chrysogenum.产黄青霉中包含青霉素基因簇的串联重复扩增的56.8 kb DNA区域的转录和生物信息学分析。
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Simultaneous utilization of glucose and gluconate in Penicillium chrysogenum during overflow metabolism.在黄曲霉属真菌 overflow 代谢过程中同时利用葡萄糖和葡萄糖酸盐。
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Casein phosphopeptides and CaCl increase penicillin production and cause an increment in microbody/peroxisome proteins in Penicillium chrysogenum.酪蛋白磷酸肽和氯化钙可提高产黄青霉的青霉素产量，并导致其微体/过氧化物酶体蛋白增加。
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Key role of LaeA and velvet complex proteins on expression of β-lactam and PR-toxin genes in Penicillium chrysogenum: cross-talk regulation of secondary metabolite pathways.拉埃A和天鹅绒复合体蛋白在产黄青霉β-内酰胺和PR毒素基因表达中的关键作用：次级代谢产物途径的相互调控
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Penicillin G production by immobilized whole cells of Penicillium chrysogenum.产黄青霉固定化全细胞生产青霉素G
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The transport of phenylacetic acid across the peroxisomal membrane is mediated by the PaaT protein in Penicillium chrysogenum.苯乙酸通过过氧化物酶体膜的运输是由产黄青霉中的 PaaT 蛋白介导的。
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Penicillium chrysogenum glucose oxidase -- a study on its antifungal effects.产黄青霉葡萄糖氧化酶——其抗真菌作用的研究
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Proteomics shows new faces for the old penicillin producer Penicillium chrysogenum.蛋白质组学揭示了产青霉素的老菌种产黄青霉的新面貌。
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Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach.乙醇限制恒化器培养产黄青霉过程中青霉素产量的退化：一种系统生物学方法。
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Penicillin.青霉素
Experientia. 1946 May 15;2:160-71. doi: 10.1007/BF02156445.
6
Drying Penicillin by Sublimation.通过升华法干燥青霉素
Br Med J. 1945 Feb 17;1(4389):216-8. doi: 10.1136/bmj.1.4389.216.
7
Preparation of Purified Penicillin.纯化青霉素的制备
Br Med J. 1945 Jan 27;1(4386):116-7. doi: 10.1136/bmj.1.4386.116.
8
[Whey and other natural substances as substrates for penicillia in penicillin production].[乳清及其他天然物质作为青霉素生产中青霉的底物]
Experientia. 1946 Oct 15;2(10):407. doi: 10.1007/BF02154216.
9
Penicillin in the treatment of diptheria.青霉素治疗白喉。
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10
Different roads to discovery; Prontosil (hence sulfa drugs) and penicillin (hence beta-lactams).不同的发现之路；百浪多息（即磺胺类药物）和青霉素（即β-内酰胺类抗生素）。
J Ind Microbiol Biotechnol. 2009 Jun;36(6):775-86. doi: 10.1007/s10295-009-0553-8. Epub 2009 Mar 13.
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The Determination of the Composition of the Different Proteins of Ox and Horse Serum by the Method of Van Slyke.用范斯莱克法测定牛和马血清中不同蛋白质的组成
Biochem J. 1914 Oct;8(5):541-52. doi: 10.1042/bj0080541.
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