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The estimation of androst-16-en-3alpha-ol in human urine. Partial synthesis of androstenol and of its beta-glucosiduronic acid.

作者信息

Brooksbank B W, Haslewood G A

机构信息

Guy's Hospital Medical School, London, S.E. 1.

出版信息

Biochem J. 1961 Sep;80(3):488-96. doi: 10.1042/bj0800488.

DOI:10.1042/bj0800488
PMID:16748922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1243258/
Abstract
摘要

相似文献

1
The estimation of androst-16-en-3alpha-ol in human urine. Partial synthesis of androstenol and of its beta-glucosiduronic acid.人尿中雄甾-16-烯-3α-醇的测定。雄烯醇及其β-葡萄糖醛酸的部分合成。
Biochem J. 1961 Sep;80(3):488-96. doi: 10.1042/bj0800488.
2
5α-Androst-16-en-3α-ol β-D-glucuronide, precursor of 5α-androst-16-en-3α-ol in human sweat.5α-雄烷-16-烯-3α-醇-β-D-葡糖苷酸，人汗中 5α-雄烷-16-烯-3α-醇的前体。
Chem Biodivers. 2013 Dec;10(12):2197-208. doi: 10.1002/cbdv.201300286.
3
Positive relationship between menstrual synchrony and ability to smell 5alpha-androst-16-en-3alpha-ol.月经同步与嗅觉5α-雄甾-16-烯-3α-醇能力之间的正相关关系。
Chem Senses. 2000 Aug;25(4):407-11. doi: 10.1093/chemse/25.4.407.
4
Development of a candidate reference method for the simultaneous quantitation of the boar taint compounds androstenone, 3α-androstenol, 3β-androstenol, skatole, and indole in pig fat by means of stable isotope dilution analysis-headspace solid-phase microextraction-gas chromatography/mass spectrometry.采用稳定同位素稀释分析-顶空固相微萃取-气相色谱/质谱法发展一种同时定量检测猪脂肪中雄烯酮、3α-雄烷醇、3β-雄烷醇、粪臭素和吲哚等公猪异味化合物的候选参考方法。
Anal Chem. 2011 Sep 1;83(17):6785-91. doi: 10.1021/ac201465q. Epub 2011 Aug 15.
5
Determination of 5alpha-androst-16-en-3alpha-ol in truffle fermentation broth by solid-phase extraction coupled with gas chromatography-flame ionization detector/electron impact mass spectrometry.采用固相萃取结合气相色谱-火焰离子化检测器/电子轰击质谱法测定松露发酵液中的5α-雄甾-16-烯-3α-醇。
J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jul 15;870(2):209-15. doi: 10.1016/j.jchromb.2008.06.014. Epub 2008 Jun 13.
6
The metabolism in man of (3H)-5alpha-16-androsten-3alpha-ol and of (3H)-5alpha-16-androsten-3-one.（3H）-5α-16-雄烯-3α-醇和（3H）-5α-16-雄烯-3-酮在人体内的代谢
Horm Res. 1978;9(5):254-70. doi: 10.1159/000178921.
7
SYNTHESIS OF 16-OXYGENATED ANDROST-5-EN-3-BETA-OL DERIVATIVES.16-氧化雄甾-5-烯-3β-醇衍生物的合成
Chem Pharm Bull (Tokyo). 1964 Jul;12:808-12. doi: 10.1248/cpb.12.808.
8
The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors.信息素雄烯醇（5α-雄甾-16-烯-3α-醇）是一种γ-氨基丁酸A型受体的神经甾体正向调节剂。
J Pharmacol Exp Ther. 2006 May;317(2):694-703. doi: 10.1124/jpet.105.098319. Epub 2006 Jan 13.
9
Androstenol, a putative human pheromone, affects human (Homo sapiens) male choice performance.雄烯醇，一种假定的人类信息素，会影响人类（智人）男性的择偶表现。
J Comp Psychol. 1987 Jun;101(2):210-2.
10
Seized designer supplement named "1-Androsterone": identification as 3β-hydroxy-5α-androst-1-en-17-one and its urinary elimination.缴获的设计师补充剂命名为“1-雄甾烯酮”：鉴定为 3β-羟基-5α-雄甾-1-烯-17-酮及其尿排泄。
Steroids. 2011 May;76(6):540-7. doi: 10.1016/j.steroids.2011.02.001. Epub 2011 Feb 16.

引用本文的文献

1
Constitutive Androstane Receptor Regulates Germ Cell Homeostasis, Sperm Quality, and Male Fertility via Akt-Foxo1 Pathway.组成型雄烷受体通过 Akt-Foxo1 通路调控生殖细胞稳态、精子质量和雄性生育力。
Adv Sci (Weinh). 2024 Nov;11(43):e2402082. doi: 10.1002/advs.202402082. Epub 2024 Sep 24.
2
URINARY 16-ANDROSTEN-3-ALPHA-OL, 17-OXOSTEROIDS AND MENTAL ILLNESS.尿16-雄烯-3α-醇、17-氧代类固醇与精神疾病
Br Med J. 1964 Jun 20;1(5398):1602-6. doi: 10.1136/bmj.1.5398.1602.
3
Estimation of the odorous steroid, 5 alpha-androst-16-en-3-one, in human saliva.
Experientia. 1983 Jul 15;39(7):790-2. doi: 10.1007/BF01990330.
4
Studies on the biosynthesis of 16-dehydro steroids. The metabolism of [4-14C]pregnenolone by boar adrenal and testis tissue in vitro.16-脱氢甾体生物合成的研究。[4-¹⁴C]孕烯醇酮在体外经公猪肾上腺和睾丸组织的代谢。
Biochem J. 1967 Aug;104(2):550-6. doi: 10.1042/bj1040550.
5
The isolation of urinary 17-oxo steroid and corticosteroid glucuronides.尿中17-氧代类固醇和皮质类固醇葡糖醛酸苷的分离
Biochem J. 1964 May;91(2):209-17. doi: 10.1042/bj0910209.
6
Steroidal free radicals as possible intermediates in the biosynthesis of C19-delta 16-steroids.甾体自由基作为C19-δ16-甾体生物合成中可能的中间体。
Proc Natl Acad Sci U S A. 1970 Dec;67(4):1754-60. doi: 10.1073/pnas.67.4.1754.
7
Studies on the metabolism of 5alpha-androst-16-en-3-one in boar tests in vivo.5α-雄甾-16-烯-3-酮在公猪睾丸内的体内代谢研究。
Biochem J. 1974 Nov;144(2):347-52. doi: 10.1042/bj1440347.

本文引用的文献

1
CLINICAL STUDIES OF THE BLOOD VOLUME. I. CLINICAL APPLICATION OF A METHOD EMPLOYING THE AZO DYE "EVANS BLUE" AND THE SPECTROPHOTOMETER.血容量的临床研究。I. 一种使用偶氮染料“伊文思蓝”和分光光度计的方法的临床应用。
J Clin Invest. 1937 May;16(3):301-16. doi: 10.1172/JCI100859.
2
Isolation of delta 16-androsten-3 (alpha)-oil from the urine of women with adrenal cortical tumors.从患有肾上腺皮质肿瘤的女性尿液中分离出δ16 - 雄甾烯 - 3(α) - 醇。
J Biol Chem. 1950 Jun;184(2):593-8.
3
The isolation of androst-16-en-3 alpha-ol from women's urine.从女性尿液中分离出雄甾-16-烯-3α-醇。
Biochem J. 1952 May;51(2):286-8. doi: 10.1042/bj0510286.
4
The nature of pregnanediol-like glucuronide.孕二醇样葡糖醛酸苷的性质。
Biochem J. 1950 Jun-Jul;47(1):36-43. doi: 10.1042/bj0470036.
5
[Steroid conjugates. III. Chemical synthesis & paper chromatographic separation of some steroid glucuronides].[甾体共轭物。III. 某些甾体葡糖醛酸苷的化学合成及纸色谱分离]
Hoppe Seylers Z Physiol Chem. 1959;314(4-6):234-9.
6
The association of adrenaline and noradrenaline with blood platelets.肾上腺素和去甲肾上腺素与血小板的关联。
Biochem J. 1958 Sep;70(1):14-22. doi: 10.1042/bj0700014.
7
Hydrolysis of ketosteroid hydrogen sulfates by solvolysis procedures.通过溶剂分解程序水解酮甾体硫酸氢盐。
J Biol Chem. 1958 Aug;233(2):331-5.
8
The enzymic hydrolysis of steroid conjugates. I. Sulphatase and beta-glucuronidase activity of molluscan extracts.类固醇结合物的酶促水解。I. 软体动物提取物的硫酸酯酶和β-葡萄糖醛酸酶活性。
Biochem J. 1956 Aug;63(4):705-10. doi: 10.1042/bj0630705.
9
Microanalysis of glucuronide glucuronic acid as applied to beta-glucuronidase and glucuronic acid studies.应用于β-葡萄糖醛酸酶和葡萄糖醛酸研究的葡萄糖醛酸苷葡萄糖醛酸的微量分析。
J Biol Chem. 1955 Aug;215(2):527-37.
10
Studies on sulphatases. 4. Arylsulphatase and beta-glucuronidase concentrates from limpets.硫酸酯酶研究。4. 帽贝中的芳基硫酸酯酶和β-葡萄糖醛酸酶浓缩物。
Biochem J. 1953 Sep;55(2):315-20. doi: 10.1042/bj0550315.