幼羊和成羊腮腺中的三磷酸腺苷酶活性与烟酰胺核苷酸辅酶
Adenosine-triphosphatase activity and nicotinamide nucleotide coenzymes in the parotid gland of the young lamb and adult sheep.
作者信息
Filsell O H, Jarrett I G
机构信息
Commonwealth Scientific and Industrial Research Organisation Division of Biochemistry and General Nutrition, University of Adelaide, Adelaide, South Australia.
出版信息
Biochem J. 1965 Nov;97(2):479-84. doi: 10.1042/bj0970479.
Abstract
- The activity of a Mg(2+)-dependent Na(+)-plus-K(+)-activated adenosine triphosphatase and the concentrations of nicotinamide nucleotide coenzymes have been measured in the immature parotid glands of young lambs and in the actively secreting glands of adult sheep. 2. The activity of the adenosine triphosphatase increased during development and attained relatively high levels in the mature secreting gland. 3. A high ([NAD]+[NADH(2)])/([NADP]+[NADPH(2)]) ratio (approx. 10:1) was observed in the parotid glands of lambs and sheep. 4. The high concentrations of NAD and the very low concentrations of NADPH(2) have been discussed in relation to metabolic activity, the activity of the Na(+)-plus-K(+)-activated adenosine triphosphatase and the secretion of saliva by the parotid gland.
摘要
- 已对幼龄羔羊未成熟腮腺以及成年绵羊活跃分泌的腮腺中镁离子依赖的钠钾激活三磷酸腺苷酶的活性和烟酰胺核苷酸辅酶的浓度进行了测定。2. 三磷酸腺苷酶的活性在发育过程中增加，并在成熟分泌腺中达到相对较高的水平。3. 在羔羊和绵羊的腮腺中观察到较高的（[NAD]+[NADH₂]）/（[NADP]+[NADPH₂]）比率（约为10:1）。4. 已结合代谢活性、钠钾激活三磷酸腺苷酶的活性以及腮腺唾液分泌对高浓度的NAD和极低浓度的NADPH₂进行了讨论。
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