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高压氧治疗可减轻炎性疼痛动物模型中的炎症和机械性超敏反应。

Hyperbaric oxygen treatment decreases inflammation and mechanical hypersensitivity in an animal model of inflammatory pain.

作者信息

Wilson Hilary D, Wilson Judy R, Fuchs Perry N

机构信息

University of Texas at Arlington, Department of Psychology, 501 S. Nedderman Drive, Arlington, TX 76019, USA.

出版信息

Brain Res. 2006 Jul 7;1098(1):126-8. doi: 10.1016/j.brainres.2006.04.088. Epub 2006 Jun 5.

DOI:10.1016/j.brainres.2006.04.088
PMID:16750177
Abstract

Hyperbaric oxygen therapy has been used to treat a variety of ailments from carbon monoxide poisoning to fibromyalgia. The purpose of this experiment was to explore the effect of hyperbaric oxygen treatment on carrageenan-induced inflammation and pain in rats. Hyperbaric oxygen treatment significantly decreased inflammation and pain following carrageenan injection. Clinically hyperbaric oxygen may be used in situations where NSAIDS are contraindicated or in persistent cases of inflammation.

摘要

高压氧疗法已被用于治疗从一氧化碳中毒到纤维肌痛等多种疾病。本实验的目的是探讨高压氧治疗对角叉菜胶诱导的大鼠炎症和疼痛的影响。高压氧治疗显著减轻了角叉菜胶注射后的炎症和疼痛。临床上，在非甾体抗炎药（NSAIDS）禁忌的情况下或在持续性炎症病例中可使用高压氧。

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