Groom L, Kendrick D, Coupland C, Patel B, Hippisley-Cox J
School of Community Health Sciences, University of Nottingham, Nottingham, UK.
Inj Prev. 2006 Jun;12(3):166-70. doi: 10.1136/ip.2005.011254.
To determine the relationship between deprivation and hospital admission rates for unintentional poisoning, by poisoning agent in children aged 0-4 years.
Cross sectional study of routinely collected hospital admissions data.
East Midlands, UK.
1469 admissions due to unintentional poisoning over two years.
Hospital admission rates for unintentional poisoning. Incidence rate ratios (IRRs) comparing hospital admission rates for poisoning in the most and least deprived electoral wards.
Children in the most deprived wards had admission rates for medicinal poisoning that were 2-3 times higher than those in the least deprived wards (IRR 2.49, 95% CI 1.87 to 3.30). Admission rates for non-medicinal poisoning were about twice as high in the most compared to the least deprived wards (IRR 1.77, 95% CI 1.19 to 2.64). Deprivation gradients were particularly steep for benzodiazepines (IRR 5.63, 95% CI 1.72 to 18.40), antidepressants (IRR 4.58, 95% CI 1.80 to 11.66), cough and cold remedies (IRR 3.93, 95% CI 1.67 to 9.24), and organic solvents (IRR 3.69, 95% CI 1.83 to 7.44).
There are steep deprivation gradients for admissions to hospital for childhood poisoning, with particularly steep gradients for some psychotropic medicines. Interventions to reduce these inequalities should be directed towards areas of greater deprivation.
确定0 - 4岁儿童因意外中毒入院率与贫困程度之间的关系,并按中毒剂进行分类。
对常规收集的医院入院数据进行横断面研究。
英国东米德兰兹地区。
两年内1469例因意外中毒入院的病例。
意外中毒的医院入院率。比较最贫困和最不贫困选区中毒入院率的发病率比(IRR)。
最贫困选区儿童药物中毒的入院率比最不贫困选区的儿童高2至3倍(IRR 2.49,95%置信区间1.87至3.30)。与最不贫困选区相比,最贫困选区非药物中毒的入院率约为两倍(IRR 1.77,95%置信区间1.19至2.64)。苯二氮卓类药物(IRR 5.63,95%置信区间1.72至18.40)、抗抑郁药(IRR 4.58,95%置信区间1.80至11.66)、止咳感冒药(IRR 3.93,95%置信区间1.67至9.24)和有机溶剂(IRR 3.69,95%置信区间1.83至7.44)的贫困梯度尤为明显。
儿童中毒入院存在明显的贫困梯度,某些精神药物的梯度尤为明显。减少这些不平等现象的干预措施应针对贫困程度较高的地区。