[骨骼及与骨相关的生化检查。骨骼和胶原蛋白相关代谢产物。抗酒石酸酸性磷酸酶（TRACP）]
[Bone and bone related biochemical examinations. Bone and collagen related metabolites. Tartrate-resistant acid phosphatase (TRACP)].
作者信息
Mochizuki Yoshiko
机构信息
Dokkyo University School of Medicine, Department of Obstetrics and Gynecology.
出版信息
Clin Calcium. 2006 Jun;16(6):948-55.
Tartrate-resistant acid phosphatase (TRACP) is a well-known marker for bone resorption, but it is not enough for clinical use in specificity of bone and instability in serum. Tartrate-resistant acid phosphatase type 5b (TRACP-5b) is an osteoclast-produced enzyme and was reported the clinical performance of a novel fragments absorbed immunocapture enzyme assay. TRACP-5b have smaller day-to-day and diurnal variation than those of urinary bone resorption markers and show the usefulness as promising markers in monitoring the treatment for osteoporosis.
抗酒石酸酸性磷酸酶（TRACP）是一种广为人知的骨吸收标志物，但在骨特异性和血清稳定性方面，它不足以用于临床。5b型抗酒石酸酸性磷酸酶（TRACP-5b）是破骨细胞产生的一种酶，有报道称其在一种新型片段吸收免疫捕获酶测定中的临床性能。与尿骨吸收标志物相比，TRACP-5b的日常和昼夜变化较小，在监测骨质疏松症治疗方面显示出有望成为有价值的标志物。
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