柳氮磺胺吡啶诱发的可逆性过敏性肺炎和致命性肺纤维化：两例报告

Sulphasalazine-induced reversible hypersensitivity pneumonitis and fatal fibrosing alveolitis: report of two cases.

作者信息

Leino R, Liippo K, Ekfors T

机构信息

Department of Medicine, Turku University, Finland.

出版信息

J Intern Med. 1991 Jun;229(6):553-6. doi: 10.1111/j.1365-2796.1991.tb00396.x.

DOI:10.1111/j.1365-2796.1991.tb00396.x

PMID:1675246

Abstract

The cases of two patients with ulcerative colitis are described who developed pulmonary infiltrates during the early months of treatment with sulphasalazine. The first patient had a hypersensitivity pneumonitis, which was confirmed by challenge. Recovery was complete. The second patient developed a fibrosing alveolitis type reaction, with fatal outcome.

摘要

描述了两名溃疡性结肠炎患者的病例，他们在使用柳氮磺胺吡啶治疗的最初几个月内出现了肺部浸润。第一名患者患有过敏性肺炎，经激发试验确诊。已完全康复。第二名患者出现了纤维化肺泡炎类型的反应，最终死亡。