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纤维化肺泡炎及柳氮磺胺吡啶治疗

Fibrosing alveolitis and treatment with sulphasalazine.

作者信息

Davies D, MacFarlane A

出版信息

Gut. 1974 Mar;15(3):185-8. doi: 10.1136/gut.15.3.185.

DOI:10.1136/gut.15.3.185
PMID:4152289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1412877/
Abstract

A woman with ulcerative colitis was treated with sulphasalazine and prednisolone. After four months' treatment she began to get short of breath and she died a month later with severe subacute fibrosing alveolitis. It is believed that the lung disease was caused by sulphasalazine and that prednisolone was not able to prevent its development. A reversible form of lung disease has previously been attributed to this drug.

摘要

一名患有溃疡性结肠炎的女性接受了柳氮磺胺吡啶和泼尼松龙治疗。治疗四个月后,她开始出现气短症状,并于一个月后死于严重的亚急性纤维性肺泡炎。据信,肺部疾病是由柳氮磺胺吡啶引起的,泼尼松龙无法阻止其发展。此前,一种可逆形式的肺部疾病被认为与此药物有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/b57fec2fe714/gut00616-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/5237ea768ed0/gut00616-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/0006c3c07674/gut00616-0034-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/ef68bcba136b/gut00616-0034-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/b616f68d34ed/gut00616-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/b57fec2fe714/gut00616-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/5237ea768ed0/gut00616-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/0006c3c07674/gut00616-0034-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/ef68bcba136b/gut00616-0034-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/b616f68d34ed/gut00616-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4c3/1412877/b57fec2fe714/gut00616-0035-a.jpg

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1
Fibrosing alveolitis and treatment with sulphasalazine.纤维化肺泡炎及柳氮磺胺吡啶治疗
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引用本文的文献

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Respir Med Case Rep. 2016 Mar 22;18:35-6. doi: 10.1016/j.rmcr.2016.03.006. eCollection 2016.
2
The association between pulmonary function impairment and colon inflammation in ulcerative colitis patients: A scientific basis for exterior-interior correlation between lung and large intestine.溃疡性结肠炎患者肺功能损害与结肠炎症之间的关联:肺与大肠表里相关的科学依据。
Chin J Integr Med. 2016 Dec;22(12):894-901. doi: 10.1007/s11655-014-1842-2. Epub 2014 Jun 18.
3
Pulmonary involvement and allergic disorders in inflammatory bowel disease.

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