Leyser Ottoline
Department of Biology, University of York, York YO10 5YW, UK.
Curr Biol. 2006 Jun 6;16(11):R424-33. doi: 10.1016/j.cub.2006.05.014.
Recent years have seen rapid progress in our understanding of the mechanism of action of the plant hormone auxin. A major emerging theme is the central importance of the interplay between auxin signalling and the active transport of auxin through the plant to create dynamic patterns of auxin accumulation. Even in tissues where auxin distribution patterns appear stable, they are the product of standing waves, with auxin flowing through the tissue, maintaining local pockets of high and low concentration. The auxin distribution patterns result in changes in gene expression to trigger diverse, context-dependent growth and differentiation responses. Multi-level feedback loops between the signal transduction network and the auxin transport network provide self-stabilising patterns that remain sensitive to the external environment and to the developmental progression of the plant. The full biological implications of the behaviour of this system are only just beginning to be understood through a combination of experimental manipulation and mathematical modelling.
近年来，我们对植物激素生长素作用机制的理解取得了迅速进展。一个主要的新出现的主题是生长素信号传导与生长素在植物体内的主动运输之间相互作用的核心重要性，以形成生长素积累的动态模式。即使在生长素分布模式看似稳定的组织中，它们也是驻波的产物，生长素在组织中流动，维持局部高浓度和低浓度区域。生长素分布模式导致基因表达变化，从而触发各种依赖于环境的生长和分化反应。信号转导网络和生长素运输网络之间的多级反馈回路提供了自我稳定模式，这些模式对外部环境和植物的发育进程仍然敏感。通过实验操作和数学建模相结合，才刚刚开始理解这个系统行为的全部生物学意义。
