来自百部的二苯乙烯类化合物。

Stilbenoids from Stemona japonica.

作者信息

Yang Xin-Zhou, Tang Chun-Ping, Ye Yang

机构信息

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, SIBS, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Zhangjiang Hightech Park, Shanghai 201203, People's Republic of China.

出版信息

J Asian Nat Prod Res. 2006 Jan-Mar;8(1-2):47-53. doi: 10.1080/10286020500382678.

DOI:10.1080/10286020500382678

PMID:16753782

Abstract

Three new dihydrostilbenes, stilbostemins J-L (1-3), and a new dihydrophenanthrene, stemanthrene F (4), were isolated from the roots of Stemona japonica together with two known bibenzyls, 3,5-dihydroxy-4-methylbibenzyl (5) and 3,5-dihydroxy-2'-methoxy-4-methylbibenzyl (6). Their structures were elucidated by spectroscopic analyses. Compounds 3-6 exhibited strong antibacterial activities against Staphylococcus aureus and Staphylococcus epidermidis.

摘要

从百部（Stemona japonica）的根部分离出三种新的二氢茋类化合物，即百部茋素J-L（1-3），以及一种新的二氢菲类化合物，百部蒽F（4），同时还分离出两种已知的联苄类化合物，3,5-二羟基-4-甲基联苄（5）和3,5-二羟基-2'-甲氧基-4-甲基联苄（6）。通过光谱分析确定了它们的结构。化合物3-6对金黄色葡萄球菌和表皮葡萄球菌表现出较强的抗菌活性。