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儿童肾肿瘤

Renal tumours in children.

作者信息

Mäkinen J, Rapola J

出版信息

Acta Pathol Microbiol Scand A. 1975 Mar;83(2):237-44. doi: 10.1111/j.1699-0463.1975.tb01380.x.

Abstract

A ten-year series of renal tumours in children up to 14 years of age was collected from the files of the Finnish Cancer Register. After histological evaluation of the material, 74 cases were accepted as primary renal tumours. Fifty-eight of these were typical Wilms' tumours, three rhabdomyosarcomas, six foetal hamartomas and seven unclassified malignant tumours. Wilms' tumours were classified into three types on the basis of the histological differentiation. The total five year survival in the Wilms group was 50 per cent with no difference between patients over and under the age of one year. Of the subtypes of Wilms' tumours the sarcomatous type showed worse prognosis than average; only three out of 16 patients were alive after a five-year follow-up time. None of the patients with foetal hamartoma died of tumour, although two fatalities, connected with the surgery, were recorded. The value of histological classification of Wilms' tumours and the importance of the recognition of the foetal hamartoma is emphasized.

摘要

从芬兰癌症登记处的档案中收集了一系列14岁及以下儿童的十年期肾肿瘤病例。对材料进行组织学评估后,74例被确认为原发性肾肿瘤。其中58例为典型的威尔姆斯瘤,3例横纹肌肉瘤,6例胎儿错构瘤,7例未分类的恶性肿瘤。威尔姆斯瘤根据组织学分化分为三种类型。威尔姆斯瘤组的总五年生存率为50%,一岁以上和一岁以下患者之间无差异。在威尔姆斯瘤的亚型中,肉瘤样型的预后比平均水平差;16例患者中只有3例在五年随访期后存活。胎儿错构瘤患者无一例死于肿瘤,尽管记录了两例与手术相关的死亡病例。强调了威尔姆斯瘤组织学分类的价值以及识别胎儿错构瘤的重要性。

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