史蒂文斯-约翰逊综合征中的结肠受累情况。
Colonic involvement in Stevens-Johnson syndrome.
作者信息
Powell N, Munro J M, Rowbotham D
机构信息
Department of Gastroenterology, Queen Elizabeth Hospital, London, UK.
出版信息
Postgrad Med J. 2006 Jun;82(968):e10. doi: 10.1136/pgmj.2005.042952.
Abstract
Severe gastrointestinal tract involvement is a rare manifestation of Stevens-Johnson syndrome (SJS). The case is described of a 17 year old man who developed SJS secondary to phenytoin. In addition to the cutaneous, ocular, and oral mucosal lesions typical of SJS, he also developed persistent, bloody diarrhoea associated with life threatening malnutrition. Serial colonoscopy showed severe and progressive colitis. He was treated with a combination of long term nutritional support, probiotic therapy, and supportive measures. He was eventually discharged from hospital six months after admission when the diarrhoea improved and he began to gain weight.
摘要
严重的胃肠道受累是史蒂文斯-约翰逊综合征（SJS）的一种罕见表现。本文描述了一名17岁男性患者，其因苯妥英钠继发SJS。除了SJS典型的皮肤、眼部和口腔黏膜病变外，他还出现了持续性血性腹泻，并伴有危及生命的营养不良。系列结肠镜检查显示严重且进行性的结肠炎。他接受了长期营养支持、益生菌治疗及支持性措施的联合治疗。入院六个月后，腹泻改善且体重开始增加，他最终出院。
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