Zou Jian-Hua, Dai Jungui, Chen Xiaoguang, Yuan Jing-Quan
Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education, Beijing 100050, PR China.
Chem Pharm Bull (Tokyo). 2006 Jun;54(6):920-1. doi: 10.1248/cpb.54.920.
A new oleanane-type triterpenoid (1) and five known pentacyclic triterpenoids (2-6) were isolated from the leaves of Excoecaria agallocha. Their structures were elucidated by spectroscopic analyses. The new compound was characterized as 3beta-[(2E,4E)-5-oxo-decadienoyloxy]-olean-12-ene (1). Compounds 1-6 were found inactive in vitro against several human cancer cell lines.
从海漆的叶子中分离出一种新的齐墩果烷型三萜(1)和五种已知的五环三萜(2 - 6)。通过光谱分析阐明了它们的结构。新化合物被鉴定为3β - [(2E,4E)-5-氧代-癸二烯酰氧基]-齐墩果-12-烯(1)。发现化合物1 - 6在体外对几种人类癌细胞系无活性。