Mondal Sumanta, Ghosh Debjit, Ramakrishna K
Department of Pharmaceutical Chemistry, GITAM Institute of Pharmacy, GITAM University, Visakhapatnam, Andhra Pradesh, India.
Department of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh, India.
Pharmacogn Rev. 2016 Jul-Dec;10(20):123-138. doi: 10.4103/0973-7847.194049.
Traditional system of medicine consists of large number of plants with various medicinal and pharmacological importances. This article provides a comprehensive review of the complete profile of an important mangrove plant L. () and elaborately describing the ethnobotany, phytochemistry, and pharmacological properties. It is used traditionally in the treatment of various diseases such as epilepsy, ulcers, leprosy, rheumatism, and paralysis. The latex obtained from the bark is poisonous in nature and may cause temporary blindness, thus it is also known as the blind-your-eye mangrove plant. Many phytoconstituents were isolated from the plant, which were mainly diterpenoids, triterpenoids, flavonoids, sterols, and few other compounds. The plant also showed many pharmacological activities such as antioxidant, antimicrobial, anti-inflammatory, analgesic, antiulcer, anticancer, antireverse transcriptase, antihistamine-release, antifilarial, DNA damage protective, antidiabetic, and antitumor protecting activities. Hence, this review could help guide researchers anticipating to undertake further investigations in these directions.
传统医学体系包含大量具有各种药用和药理重要性的植物。本文全面综述了一种重要的红树林植物L. ()的完整概况，并详细描述了其民族植物学、植物化学和药理特性。它在传统上用于治疗各种疾病，如癫痫、溃疡、麻风病、风湿病和瘫痪。从树皮中获取的乳胶本质上有毒，可能导致暂时失明，因此它也被称为致盲红树林植物。从该植物中分离出了许多植物成分，主要是二萜类、三萜类、黄酮类、甾醇类以及其他一些化合物。该植物还表现出许多药理活性，如抗氧化、抗菌、抗炎、镇痛、抗溃疡、抗癌、抗逆转录酶、抗组胺释放、抗丝虫、DNA损伤保护、抗糖尿病和抗肿瘤保护活性。因此，本综述有助于指导期望在这些方向上进行进一步研究的研究人员。
