Cook Linda S, Kmet Leanne M, Magliocco Anthony M, Weiss Noel S
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Epidemiology. 2006 Jul;17(4):469-72. doi: 10.1097/01.ede.0000221026.49643.cf.
Endometrial cancer incidence is lower but mortality is higher among black relative to white women. This disparity results from a relatively higher level of case-fatality in African Americans. We investigated whether the inter-racial difference in survival has diminished in more recent birth cohorts.
Women diagnosed with endometrial malignancies during 1977-1996 were identified from the U.S. Surveillance, Epidemiology and End Results program (45,261 white and 1986 black women). We calculated cumulative 5-year relative survival for 6 birth cohorts.
Survival was relatively higher in younger women than older women and in women diagnosed in earlier years compared with more recent years. Higher survival was evident in more recent birth cohorts for groups of women 60+ years of age and in all time periods, particularly for black women.
Although black women with endometrial cancer have a poorer prognosis than white women, the inter-racial difference in survival has narrowed in more recent birth cohorts.
与白人女性相比,黑人女性子宫内膜癌的发病率较低,但死亡率较高。这种差异是由于非裔美国人的病例死亡率相对较高。我们调查了在最近出生队列中,种族间的生存差异是否有所减小。
从美国监测、流行病学和最终结果计划中识别出1977年至1996年期间被诊断为子宫内膜恶性肿瘤的女性(45261名白人女性和1986名黑人女性)。我们计算了6个出生队列的累积5年相对生存率。
年轻女性的生存率相对高于老年女性,早年诊断的女性生存率高于近年诊断的女性。在60岁及以上的女性群体中,最近出生队列的生存率更高,在所有时间段都是如此,尤其是黑人女性。
虽然患有子宫内膜癌的黑人女性预后比白人女性差,但在最近出生队列中,种族间的生存差异已经缩小。