Li XueLian, Zheng SaiHua, Chen ShangJie, Qin Feng, Lau Sandy, Chen Qi
The Hospital of Obstetrics and Gynaecology, Fudan University, 419 Fangxie Road, Shanghai, China.
Tumour Biol. 2015 Jul;36(7):4961-6. doi: 10.1007/s13277-015-3143-6. Epub 2015 Feb 4.
The incidence and the trend of gynaecological cancers have been suggested to vary by ethnicity and geographical regions. Whether the incidence and type of gynaecological cancers in China is different have not been fully investigated. In this study, we reported the trend of gynaecological cancers in China. Data on 13,518 women with gynaecological cancers were collected from the largest obstetrics and gynaecology hospital in China from 2003 to 2013. Data included age at diagnosis and the annual number of women with diagnosed endometrial, ovarian, cervical cancer and other gynaecological cancers. The number of women with diagnosed gynaecological cancers increased by almost sixfold in 2013 compared to that in 2003. It was largely due to the increase of women with newly diagnosed cervical cancer. The percentage of women with endometrial and ovarian cancer within total gynaecological cancers was decreased, whilst the percentage of cervical cancer significantly increased between 2003 and 2013. The mean age of women with endometrial or ovarian cancer at diagnosis was 53 or 48 years, respectively, which was no difference over 11 years. However, the mean age of women with cervical cancer at diagnosis was significantly delayed from 42 years in 2003 to 46 years since 2011. This was also confirmed by the age-specific distribution of gynaecological cancers over 11 years. Our study found that the age onset of endometrial and ovarian cancer has not changed over 11 years. But the age onset of cervical cancer is delayed since 2011 in China.
妇科癌症的发病率和趋势被认为因种族和地理区域而异。中国妇科癌症的发病率和类型是否不同尚未得到充分研究。在本研究中,我们报告了中国妇科癌症的趋势。2003年至2013年期间,从中国最大的妇产科医院收集了13518例妇科癌症患者的数据。数据包括诊断时的年龄以及诊断为子宫内膜癌、卵巢癌、宫颈癌和其他妇科癌症的女性年度人数。与2003年相比,2013年诊断为妇科癌症的女性人数增加了近六倍。这主要是由于新诊断宫颈癌的女性人数增加。2003年至2013年期间,子宫内膜癌和卵巢癌患者在妇科癌症总数中的百分比下降,而宫颈癌的百分比显著增加。诊断为子宫内膜癌或卵巢癌的女性的平均年龄分别为53岁或48岁,11年间没有差异。然而,诊断为宫颈癌的女性的平均年龄从2003年的42岁显著推迟到2011年以来的46岁。这也得到了11年间妇科癌症年龄别分布的证实。我们的研究发现,子宫内膜癌和卵巢癌的发病年龄在11年间没有变化。但自2011年以来,中国宫颈癌的发病年龄有所推迟。