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一名复发多发性骨髓瘤合并快速进展性肺癌的造血干细胞移植受者感染人偏肺病毒。

Human metapneumovirus infection in a hematopoietic stem cell transplant recipient with relapsed multiple myeloma and rapidly progressing lung cancer.

作者信息

Huck B, Egger M, Bertz H, Peyerl-Hoffman G, Kern W V, Neumann-Haefelin D, Falcone V

机构信息

Department of Virology, Institute for Medical Microbiology and Hygiene, University Hospital Freiburg, Freiburg, Germany.

出版信息

J Clin Microbiol. 2006 Jun;44(6):2300-3. doi: 10.1128/JCM.00152-06.

DOI:10.1128/JCM.00152-06
PMID:16757646
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1489415/
Abstract

Human metapneumovirus (HMPV) was isolated from a 63-year-old multiple myeloma patient who had undergone hematopoietic stem cell transplantation and who presented with lower respiratory tract infection several weeks prior to the diagnosis of lung cancer. The isolate was phylogenetically and biologically characterized and compared to HMPV prototypes and recent pediatric isolates. Remarkably, it belonged to the novel genomic subgroup A2b.

摘要

人偏肺病毒(HMPV)是从一名63岁的多发性骨髓瘤患者体内分离出来的,该患者接受了造血干细胞移植,在被诊断出肺癌前几周出现了下呼吸道感染。对该分离株进行了系统发育和生物学特征分析,并与HMPV原型株和近期的儿科分离株进行了比较。值得注意的是,它属于新的基因组亚群A2b。

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本文引用的文献

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