Sitalakshmi S, Srikrishna Anuradha, Devi Shanthala, Damodar Prema, Alexander Betty
Department of Pathology, St. John's Medical College, Sarjapura Road, Bangalore.
Indian J Pathol Microbiol. 2005 Apr;48(2):173-6.
The bone marrow examination is invaluable in the diagnosis of certain haematological and non haematological conditions. The diagnosis of haematological disorders is achieved mainly by the examination of peripheral blood and bone marrow aspirate smears. Although bone marrow histology can provide additional information, for many technical reasons, trephines are not so popular and their diagnostic value is overlooked. Our experiences in the role of trephine biopsies in the diagnosis are presented in this article. All the bone marrow biopsies performed at the St. John's Medical College Hospital over the last 12 years (1990-2002) were reviewed The bone marrow biopsies were grouped into 3 categories for analysis. The trephine biopsy is invaluable in cases where the aspirate fails or is a dry tap as in the case of myelofibrosis, focal marrow involvement as in granulomatous lesions, metastatic tumour and lymphomas.
骨髓检查在某些血液系统和非血液系统疾病的诊断中具有重要价值。血液系统疾病的诊断主要通过外周血和骨髓穿刺涂片检查来实现。尽管骨髓组织学检查可以提供额外信息，但由于诸多技术原因，骨髓活检并不那么常用，其诊断价值也被忽视。本文介绍了我们在骨髓活检诊断中的经验。回顾了圣约翰医学院医院过去12年（1990 - 2002年）进行的所有骨髓活检。将骨髓活检分为3类进行分析。在穿刺失败或干抽的情况下，如骨髓纤维化、肉芽肿性病变、转移性肿瘤和淋巴瘤等局灶性骨髓受累的病例中，骨髓活检具有重要价值。
