Navone R, Colombano M T
Appl Pathol. 1984;2(5):264-71.
Out of 3,173 bone marrow biopsies, we found 138 cases (4.3%) of 'dry tap' aspirations: 35/218 (16%) acute leukemias, 44/445 (9.8%) myeloproliferative syndromes, 29/328 (8.8%) malignant lymphomas and Hodgkin's diseases, 10/208 (4.8%) myelomas and 10/74 (13.5%) metastatic carcinomas. Histology showed that the most common changes associated with scanty yield aspirations were bone marrow fibrosis (patchy or diffuse) and hypercellularity (especially if due to immature cells). None of the 'dry tap' cases showed normal bone marrow by trephine biopsy. It is concluded that the finding of a 'dry tap' should never be dismissed as being due to faulty technique and always needs a bone marrow biopsy.
在3173例骨髓活检中，我们发现138例（4.3%）“干抽”：218例急性白血病中有35例（16%），445例骨髓增殖性综合征中有44例（9.8%），328例恶性淋巴瘤和霍奇金病中有29例（8.8%），208例骨髓瘤中有10例（4.8%），74例转移性癌中有10例（13.5%）。组织学检查显示，与取材不足相关的最常见变化是骨髓纤维化（片状或弥漫性）和细胞增多（特别是由于未成熟细胞导致）。所有“干抽”病例经环钻活检均未显示正常骨髓。结论是，“干抽”的发现绝不应被视为是由于技术失误所致，始终需要进行骨髓活检。
