Rossano Joseph W, Quan Linda, Kenney Melanie A, Rea Thomas D, Atkins Dianne L
Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Resuscitation. 2006 Jul;70(1):80-9. doi: 10.1016/j.resuscitation.2005.10.031. Epub 2006 Jun 8.
To investigate the energy dose used to treat out-of-hospital pediatric ventricular fibrillation and the survival rates of these patients.
We reviewed three emergency medical systems (EMS) for their reports of patients under 1 month to 18 years who received shocks for ventricular fibrillation to determine the energy of each shock as well as other patient and care characteristics. Each patient's weight was estimated at the age-appropriate 50th and 95th percentiles. Patients were then grouped as receiving recommended energy doses (2 to < or = 4 J/kg), moderately high energy doses (> 4-6 J/kg), and high energy doses (> 6 J/kg).
Of 57 patients identified, 54% were male, with a mean age of 11 years, range 2 months to 17 years. Ventricular fibrillation was the initial rhythm in 80% (43/54) of patients. The mean number of shocks delivered was 3, with < or = 2 shocks delivered to 28 (49%) and > or = 5 shocks delivered to 10 (18%) patients. When evaluating all 185 shocks using the 50th percentile estimated weight, 45 (24%) shocks were at recommended doses, 56 (30%) were at moderately high energy doses, and 84 (45%) were high energy doses. Elevated energy dose was associated with an increasing number of shocks and lack of bystander CPR (p < .05). Nineteen (33%) patients survived to hospital discharge having received total doses up to 73 J/kg. Energy dose was not related to survival.
In this observational, multicenter out of hospital experience, children received a wide range of defibrillation doses, often exceeding recommended doses and equivalent to adult energy levels. Survival occurred at low and very high energy doses.
探讨用于治疗院外小儿心室颤动的能量剂量以及这些患者的生存率。
我们回顾了三个急救医疗系统(EMS)关于1个月至18岁因心室颤动接受电击治疗患者的报告,以确定每次电击的能量以及其他患者和治疗特征。根据年龄对应的第50和第95百分位数估计每位患者的体重。然后将患者分为接受推荐能量剂量(2至<或=4 J/kg)、中等高能量剂量(>4 - 6 J/kg)和高能量剂量(>6 J/kg)组。
在确定的57例患者中,54%为男性,平均年龄11岁,范围为2个月至17岁。80%(43/54)的患者心室颤动为初始心律。平均电击次数为3次,28例(49%)患者接受≤2次电击,10例(18%)患者接受≥5次电击。使用第50百分位数估计体重评估所有185次电击时,45次(24%)电击为推荐剂量,56次(30%)为中等高能量剂量,84次(45%)为高能量剂量。能量剂量升高与电击次数增加和缺乏旁观者心肺复苏相关(p <.05)。19例(33%)患者存活至出院,接受的总剂量高达73 J/kg。能量剂量与生存率无关。
在这项观察性多中心院外研究中,儿童接受了广泛的除颤剂量,常常超过推荐剂量且相当于成人能量水平。低能量剂量和非常高能量剂量时均有患者存活。