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自身免疫性边缘叶脑炎导致癫痫发作、快速进展的意识模糊和低钠血症。

Autoimmune limbic encephalitis causing fits, rapidly progressive confusion and hyponatraemia.

作者信息

Dunstan Edmund James, Winer John B

机构信息

West Heath Hospital, Rednal Road, West Heath, Birmingham B38 8 HR, UK.

出版信息

Age Ageing. 2006 Sep;35(5):536-7. doi: 10.1093/ageing/afl045. Epub 2006 Jun 8.

Abstract

A 78-year-old woman presented with a short history of confusion and seizures and was found to be hyponatraemic. Routine investigations failed to find a cause. Magnetic resonance imaging showed encephalitic changes in the temporal lobes, and voltage-gated potassium-channel antibodies were found in her blood in high titre. Although rare, this condition is important because it may respond to immunosuppression.

摘要

一名78岁女性,因出现短期意识模糊和癫痫发作就诊,检查发现存在低钠血症。常规检查未找到病因。磁共振成像显示颞叶有脑炎样改变,且在其血液中发现高滴度的电压门控钾通道抗体。尽管这种情况罕见,但很重要,因为它可能对免疫抑制治疗有反应。

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