Priftis Kostas N, Paliatsos Athanasios G, Panagiotopoulou-Gartagani Polytimi, Tapratzi-Potamianou Polyxeni, Zachariadi-Xypolita Asimina, Nicolaidou Polyxeni, Saxoni-Papageorgiou Photini
Department of Allergy-Pneumonology, Penteli Children's Hospital, P Penteli, Greece.
Respiration. 2006;73(6):783-90. doi: 10.1159/000093817. Epub 2006 Jun 7.
The association between asthma morbidity and meteorological conditions is well documented, but it is not clear to what extent more specific meteorological variables are implicated.
This study was aiming to investigate whether there is any association between specific meteorological conditions and the seasonal variation and the rate of asthma admissions among children in Athens.
Data were obtained retrospectively from hospital registries of the three main Children's Hospitals in Athens during a 23-year period (1978-2000). The meteorological database consisted of mean monthly values of eight meteorological variables. The whole period studied was divided into three time periods: 1978-1987, 1988-1993 and 1994-2000.
A clear seasonal trend with a permanent pattern was detected. There were more monthly asthma admissions in winter-spring and autumn for younger children, as well as a lower peak in winter and autumn and a major one in May for older children, without significant differences in between the three time periods. The results of a multiple regression analysis revealed that relative humidity and atmospheric pressure were predictors of up to 56.7% (1988-1993) and 59.2% (1994-2000) monthly asthma admissions among younger children. No relation of the time trend in asthma admissions during the periods studied for any age group with any of the meteorological variables was detected.
Our results indicate a constant seasonal variability in asthma admissions among children in Athens, whereas relative humidity and atmospheric pressure are the more implicated meteorological variables for younger asthmatic children.
哮喘发病率与气象条件之间的关联已有充分记录，但尚不清楚更具体的气象变量在多大程度上与之相关。
本研究旨在调查雅典儿童特定气象条件与哮喘季节性变化及哮喘入院率之间是否存在关联。
回顾性收集雅典三家主要儿童医院23年期间（1978 - 2000年）的医院登记数据。气象数据库包含八个气象变量的月均值。研究的整个时间段分为三个时期：1978 - 1987年、1988 - 1993年和1994 - 2000年。
检测到明显的季节性趋势且模式固定。年幼儿童在冬春和秋季的每月哮喘入院人数更多，而年长儿童在冬季和秋季有较低峰值，在五月有一个主要峰值，三个时期之间无显著差异。多元回归分析结果显示，相对湿度和大气压力分别是年幼儿童每月哮喘入院人数的预测因素，在1988 - 1993年可达56.7%，在1994 - 2000年可达59.2%。在所研究的时期内，未检测到任何年龄组哮喘入院时间趋势与任何气象变量之间的关系。
我们的结果表明雅典儿童哮喘入院存在持续的季节性变化，而相对湿度和大气压力是年幼儿童哮喘患者中更相关的气象变量。
