Sanli Arif, Aydin Sedat, Ateş Günay, Eken Mehmet, Celebi Ozlem
Department of Otolaryngology, Dr. Lütfi Kirdar Kartal Training and Research Hospital, Istanbul, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2006;16(2):60-3.
The aim of this study was to compare the usefulness of nasal smear eosinophilia with skin prick test for the diagnosis of allergic rhinitis and to determine the degree of correlation between the tests.
Forty-one patients (16 males, 25 females; mean age 35.17; range 14 to 56 years) with a clinical history suggestive of nasal allergy and fifteen controls (7 males, 8 females; mean age 27.6; range 16 to 40 years) without any history of allergy were enrolled in this study. Skin sensitivity tests were applied in both groups. Nasal smear was examined by light microscopy.
A positive skin test reaction was demonstrated in 73.2% of the study group and in 20% of the controls, whereas 73.2% of the patients and 13.3% of the controls demonstrated significant nasal smear eosinophilia. There was 25.5% correlation between the skin prick test and nasal smear eosinophilia, although this was not statistically significant.
Both the skin prick test and nasal smear eosinophilia showed correlation with clinical history, but there was no statistically significant correlation between the two tests.
本研究旨在比较鼻涂片嗜酸性粒细胞增多症与皮肤点刺试验在变应性鼻炎诊断中的有用性，并确定两种试验之间的相关程度。
本研究纳入了41例有鼻过敏临床病史的患者（16例男性，25例女性；平均年龄35.17岁；范围14至56岁）和15例无任何过敏史的对照者（7例男性，8例女性；平均年龄27.6岁；范围16至40岁）。两组均进行了皮肤敏感性试验。鼻涂片采用光学显微镜检查。
研究组中73.2%的患者皮肤试验反应阳性，对照组中20%的患者阳性；而73.2%的患者和13.3%的对照者鼻涂片显示明显的嗜酸性粒细胞增多。皮肤点刺试验与鼻涂片嗜酸性粒细胞增多症之间存在25.5%的相关性，尽管这在统计学上无显著意义。
皮肤点刺试验和鼻涂片嗜酸性粒细胞增多症均与临床病史相关，但两种试验之间无统计学上的显著相关性。
