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中耳黏膜原发性恶性黑色素瘤:一例报告

Primary malignant melanoma of the middle ear mucosa: a case report.

作者信息

Oztürk Ozmen, Bağlam Tekin, Uneri Cüneyd, Küllü Sevgi

机构信息

Department of Otolaryngology, Medicine Faculty of Marmara University, Istanbul, Turkey.

出版信息

Kulak Burun Bogaz Ihtis Derg. 2006;16(2):83-6.

PMID:16763422
Abstract

Primary involvement of the middle ear and mastoid mucosa by malignant melanoma (MM) has been rarely reported. We report an 81-year-old Caucasian woman presenting with otalgia, left-sided aural fullness, and hearing loss. Otoscopic examination revealed a purple-colored polyp that appeared to be vascular, occupy left external auditory canal (EAC). The computed tomography scanning showed a mass in soft tissue density, filling the tympanic and mastoid cavities, eroding the mastoid cortex, and invading medial and central parts of the EAC. A biopsy was performed with the diagnosis of MM. The patient underwent subtotal temporal bone resection with radical neck dissection. Dacarbazine was given postoperatively. The case presented herein emphasizes the need to be aware that MMs can arise in the middle ear and mastoid cavity. An index of suspicion in the differential diagnosis of temporal bone tumors is necessary for early recognition.

摘要

恶性黑色素瘤(MM)原发累及中耳和乳突黏膜的情况鲜有报道。我们报告一名81岁的白种女性,她出现耳痛、左耳闷胀感和听力损失。耳镜检查发现一个紫色息肉,似乎有血管,占据左侧外耳道(EAC)。计算机断层扫描显示软组织密度肿块,填充鼓室和乳突腔,侵蚀乳突皮质,并侵犯EAC的内侧和中央部分。进行活检后诊断为MM。患者接受了颞骨次全切除并根治性颈清扫术。术后给予达卡巴嗪。本文介绍的病例强调需要意识到MM可发生于中耳和乳突腔。在颞骨肿瘤的鉴别诊断中保持怀疑指数对于早期识别很有必要。

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Malignant melanoma of the external auditory canal.外耳道恶性黑色素瘤。
J Clin Diagn Res. 2014 Aug;8(8):FD04-6. doi: 10.7860/JCDR/2014/8841.4719. Epub 2014 Aug 20.
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Laryngoscope. 2014 Jun;124(6):E241-4. doi: 10.1002/lary.24507.