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外耳道恶性黑色素瘤。

Malignant melanoma of the external auditory canal.

作者信息

Gowthami Chebrolu, Kumar Prasanna, Ravikumar A, Joseph Leena Dennis, Rajendiran Swaminathan

机构信息

MBBS Student, Sri Ramachandra University , Porur, Chennai, India .

Associate Professor, Department of ENT, Porur,Chennai, India .

出版信息

J Clin Diagn Res. 2014 Aug;8(8):FD04-6. doi: 10.7860/JCDR/2014/8841.4719. Epub 2014 Aug 20.

Abstract

Primary malignant melanoma of the external auditory canal is rarely reported. Malignant melanoma of the ear is estimated to occur in 1-4% of all skin melanomas and about 7-20% of melanomas of the head and neck region. The pathophysiology of these tumours is different from other skin lesions because of their anatomical and functional characteristics. The case presented is of a 11 year old female child with malignant melanoma of the external auditory canal confined to the right side, who initially presented with right ear pain, bleeding, post auricular swelling and also a mass in the external auditory canal which was thought to be an aural polyp in the right ear. Excision of the tumour was accomplished by a radical mastoidectomy. It was confirmed to be malignant melanoma after histopathological examination and Immunohistochemistry. Despite all efforts, the patient succumbed to the disease after receiving three cycles of chemotherapy. Even though this malignancy is rarely found in the external auditory canal, it should be expanded into the differential diagnosis of an aural polyp and a post aural abscess. The incidence, symptoms, investigations, treatment and prognosis of malignant melanoma of the external auditory canal is discussed in this article.

摘要

外耳道原发性恶性黑色素瘤鲜有报道。耳部恶性黑色素瘤估计占所有皮肤黑色素瘤的1% - 4%,占头颈部黑色素瘤的7% - 20%左右。由于其解剖和功能特点,这些肿瘤的病理生理学与其他皮肤病变不同。本文介绍的病例是一名11岁女童,右侧外耳道恶性黑色素瘤,最初表现为右耳疼痛、出血、耳后肿胀,外耳道还有一个肿物,最初被认为是右耳的耳息肉。通过根治性乳突切除术切除肿瘤。经组织病理学检查和免疫组织化学检查确诊为恶性黑色素瘤。尽管全力治疗,患者在接受三个周期化疗后仍死于该疾病。尽管这种恶性肿瘤在外耳道很少见,但在耳息肉和耳后脓肿的鉴别诊断中应予以考虑。本文讨论了外耳道恶性黑色素瘤的发病率、症状、检查、治疗及预后。

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