Sanchez Travis H, Gallagher Kathleen M
Centers for Disease Control and Prevention National Center for HIV, STD and TB Prevention Division of HIV/AIDS Prevention-Surveillance and Epidemiology, Atlanta, GA 30333, USA.
J Acquir Immune Defic Syndr. 2006 May;42(1):95-100. doi: 10.1097/01.qai.0000218361.36335.77.
Previous studies reported associations between sildenafil (Viagra; Pfizer, New York, NY) use and risk behaviors among men who have sex with men (MSM) in limited geographic areas or special populations. The purpose of the present study was to examine Viagra use among a broader MSM population.
The 2002 HIV Testing Survey data from MSM recruited at bars in 10 US states was used to examine Viagra use in the 12 months preceding the interview. Independent correlates of Viagra use were identified using logistic regression.
Eleven percent (131/1177) of MSM reported recent Viagra use. Users were older (adjusted odds ratios [aOR] = 2.4 to 6.2, 95% CI: 1.2 to 13.6); were more likely be infected with HIV (aOR = 2.0, CI: 1.0 to 3.9); reported more male sex partners (aOR = 2.4 to 2.7, CI: 1.2 to 5.4); were twice as likely to have unprotected anal intercourse with a nonprimary male partner (aOR = 2.1, CI: 1.2 to 3.5); and were 3 times more likely to report illicit drug usage (aOR = 3.1, CI: 1.9 to 5.2). Fifty-three percent (70/131) of Viagra users simultaneously took illicit drugs.
Among MSM from numerous US cities, Viagra use is common and is associated with several high-risk behaviors. These findings are consistent with previous reports and emphasize the need for additional prevention counseling for MSM that incorporates messages targeting Viagra usage and risk behavior.
先前的研究报告了在有限的地理区域或特殊人群中,使用西地那非(万艾可;辉瑞公司,纽约州纽约市)与男男性行为者(MSM)的风险行为之间的关联。本研究的目的是在更广泛的男男性行为者人群中调查万艾可的使用情况。
使用2002年在美国10个州的酒吧招募的男男性行为者的HIV检测调查数据,来调查访谈前12个月内万艾可的使用情况。使用逻辑回归确定万艾可使用的独立相关因素。
11%(131/1177)的男男性行为者报告近期使用过万艾可。使用者年龄较大(调整后的优势比[aOR]=2.4至6.2,95%置信区间:1.2至13.6);感染HIV的可能性更高(aOR=2.0,置信区间:1.0至3.9);报告的男性性伴侣更多(aOR=2.4至2.7,置信区间:1.2至5.4);与非主要男性伴侣进行无保护肛交的可能性是两倍(aOR=2.1,置信区间:1.2至3.5);报告使用非法药物的可能性是三倍(aOR=3.1,置信区间:1.9至5.2)。53%(70/131)的万艾可使用者同时使用非法药物。
在来自美国众多城市的男男性行为者中,万艾可的使用很常见,并且与多种高风险行为相关。这些发现与先前的报告一致,并强调需要为男男性行为者提供更多的预防咨询,其中纳入针对万艾可使用和风险行为的信息。