男男性行为者中物质使用、勃起功能障碍药物与近期HIV感染之间的关联。
Associations between substance use, erectile dysfunction medication and recent HIV infection among men who have sex with men.
作者信息
Drumright Lydia N, Gorbach Pamina M, Little Susan J, Strathdee Steffanie A
机构信息
Division of International Health and Cross-Cultural Medicine, Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, Mail code 0622, La Jolla, CA 92093, USA.
出版信息
AIDS Behav. 2009 Apr;13(2):328-36. doi: 10.1007/s10461-007-9330-8. Epub 2007 Dec 7.
Abstract
We conducted a case-control study to compare illicit substance and erectile dysfunction medication (EDM) use between recently HIV-infected and uninfected men who have sex with men (MSM). Eighty-six recently (previous 12 months) HIV-infected MSM (cases) and 59 MSM who recently tested HIV-negative (controls) completed computer-assisted self-interviews. There were no statistical differences in demographics or number of sexual partners by HIV status. Cases were more likely than controls to report methamphetamine or nitrite use, but not EDM, gamma hydroxybutyrate, 3,4 methylenedioxymethamphetamine, cocaine, or marijuana use, in the previous 12 months and with their last three sexual partners in multivariate logistic regression models. Use of nitrites and amphetamine may increase HIV risk among MSM.
摘要
我们开展了一项病例对照研究，以比较近期感染HIV与未感染HIV的男男性行为者（MSM）之间非法药物及勃起功能障碍药物（EDM）的使用情况。86名近期（过去12个月内）感染HIV的男男性行为者（病例组）和59名近期HIV检测呈阴性的男男性行为者（对照组）完成了计算机辅助的自我访谈。按HIV感染状况分类，两组在人口统计学特征或性伴侣数量方面无统计学差异。在多因素逻辑回归模型中，病例组比对照组更有可能报告在过去12个月内以及与最近三个性伴侣发生性行为时使用过甲基苯丙胺或亚硝酸盐，但EDM、γ-羟基丁酸、3,4-亚甲基二氧基甲基苯丙胺、可卡因或大麻的使用情况并非如此。使用亚硝酸盐和苯丙胺可能会增加男男性行为者感染HIV的风险。
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