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来自特定地理区域人群的成人重症监护病房使用情况的人口统计学和临床差异。

Demographic and clinical variation of adult intensive care unit utilization from a geographically defined population.

作者信息

Seferian Edward G, Afessa Bekele

机构信息

Division of Pediatric Critical Care Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

出版信息

Crit Care Med. 2006 Aug;34(8):2113-9. doi: 10.1097/01.CCM.0000227652.08185.A4.

Abstract

OBJECTIVE

To determine population-based rates of adult intensive care unit (ICU) use and evaluate the effects that demographic variables and chronic illness have on ICU utilization.

DESIGN

Retrospective, population-based cohort study.

SETTING

Olmsted County, Minnesota.

PARTICIPANTS

Adult residents admitted to an ICU in 1998.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

Measurements included demographics, Acute Physiology and Chronic Health Evaluation III score, ICU admission diagnosis, ICU interventions, Charlson comorbidity index and conditions, ICU length of stay (LOS), and ICU, hospital, 1-month, and 1-yr mortalities. Risk of ICU admission and rates of ICU utilization increased substantially with increasing age, peaking in the very elderly. The rates of ICU admission and utilization in those > or =85 yrs old were 58.2 admissions/1,000 residents and 195.8 days/1,000 residents compared with 3.8 admissions/1,000 residents and 11.5 days/1,000 residents in those 18 to 44 yrs old. Residents > or =85 yrs old were 3.75 times as likely (p < .001) to be admitted to the ICU compared with those 18-44 yrs old after controlling for the presence of comorbid illness. ICU admission rates increased with an increasing number of comorbid illnesses. Residents with cardiovascular conditions and renal disease had high rates of ICU admission. Repeat users of the ICU were more likely to have a chronic condition and higher degree of comorbid illness compared with nonrepeat users. ICU mortality was similar across all age groups, except in those > or =85 yrs old, for whom mortality was greater. One-year mortality after ICU admission increased with increasing age.

CONCLUSIONS

Population-based rates of ICU admission and utilization in Olmsted County, Minnesota, increased with age and are highest in the very elderly. The presence of chronic illness, particularly cardiovascular conditions, significantly increases ICU utilization and risk of ICU admission.

摘要

目的

确定基于人群的成人重症监护病房(ICU)使用率,并评估人口统计学变量和慢性疾病对ICU使用情况的影响。

设计

回顾性、基于人群的队列研究。

地点

明尼苏达州奥尔姆斯特德县。

参与者

1998年入住ICU的成年居民。

干预措施

无。

测量指标及主要结果

测量指标包括人口统计学特征、急性生理学与慢性健康状况评估III评分、ICU入院诊断、ICU干预措施、查尔森合并症指数及病情、ICU住院时间(LOS)以及ICU、医院、第1个月和第1年的死亡率。随着年龄增长,ICU入院风险和使用率大幅上升,在高龄人群中达到峰值。85岁及以上人群的ICU入院率为58.2例/1000居民,使用天数为195.8天/1000居民,而18至44岁人群的入院率为3.8例/1000居民,使用天数为11.5天/1000居民。在控制合并症存在的情况下,85岁及以上居民入住ICU的可能性是18至44岁居民的3.75倍(p <.001)。ICU入院率随合并症数量的增加而上升。患有心血管疾病和肾病的居民ICU入院率较高。与非重复使用者相比,ICU的重复使用者更有可能患有慢性病且合并症程度更高。除85岁及以上人群死亡率较高外,所有年龄组的ICU死亡率相似。ICU入院后的1年死亡率随年龄增长而增加。

结论

明尼苏达州奥尔姆斯特德县基于人群的ICU入院率和使用率随年龄增长而上升,在高龄人群中最高。慢性病的存在,尤其是心血管疾病,显著增加了ICU的使用率和入院风险。

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