Dinesh D, Baker B, Carter J M
New Zealand Blood Service, Wellington, New Zealand.
Transfus Med. 2006 Jun;16(3):206-8. doi: 10.1111/j.1365-3148.2006.00668.x.
Paroxysmal nocturnal haemoglobinuria (PNH) is a rare acquired haemolytic anaemia. Cardiac bypass surgery in patients with PNH may be complicated by aggravation of haemolysis in addition to increased risk of infection, renal failure, bleeding and thrombosis. We describe a case of uncomplicated cardiopulmonary bypass surgery for aortic valve replacement and aortoplasty in a patient with PNH and discuss some recommendations to reduce the risk of peri-operative complications.
阵发性睡眠性血红蛋白尿（PNH）是一种罕见的获得性溶血性贫血。PNH患者进行心脏搭桥手术时，除了感染、肾衰竭、出血和血栓形成风险增加外，还可能因溶血加重而出现并发症。我们描述了一例PNH患者进行主动脉瓣置换和主动脉成形术的非复杂性体外循环手术，并讨论了一些降低围手术期并发症风险的建议。
