Wachowiak Matt, Shipley Michael T
Department of Biology, Boston University, Boston, MA 02215, USA.
Semin Cell Dev Biol. 2006 Aug;17(4):411-23. doi: 10.1016/j.semcdb.2006.04.007. Epub 2006 May 5.
Input from olfactory receptor neurons is first organized and processed in the glomerular layer of the olfactory bulb. Olfactory glomeruli serve as functional units in coding olfactory information and contain a complex network of synaptic connections. Odor information has long been thought to be represented by spatial patterns of glomerular activation; recent work has, additionally, shown that these patterns are temporally dynamic. At the same time, recent advances in our understanding of the glomerular network suggest that glomerular processing serves to temporally sharpen these dynamics and to modulate spatial patterns of glomerular activity. We speculate that odor representations and their postsynaptic processing are tuned to and shaped by the sniffing behavior of the animal.
嗅觉受体神经元的输入首先在嗅球的肾小球层进行组织和处理。嗅觉小球作为编码嗅觉信息的功能单元，包含复杂的突触连接网络。长期以来，气味信息一直被认为是由小球激活的空间模式来表示的；最近的研究还表明，这些模式在时间上是动态的。与此同时，我们对小球网络理解的最新进展表明，小球处理有助于在时间上锐化这些动态变化，并调节小球活动的空间模式。我们推测，气味表征及其突触后处理是根据动物的嗅吸行为进行调整和塑造的。
