Nakagawa Tomoya, Maeda Naoyuki, Okazaki Noriko, Hori Yuichi, Nishida Kohji, Tano Yasuo
Department of Ophthalmology, Osaka University Medical School, Suita, Japan.
Am J Ophthalmol. 2006 Jun;141(6):1134-6. doi: 10.1016/j.ajo.2005.12.043.
To investigate the possible factors involved in the development of acute hydrops in patients with keratoconus.
Prospective interventional case series.
Thirteen consecutive keratoconic eyes of 13 patients with acute hydrops were examined by ultrasound biomicroscopy (UBM).
Ultrasound biomicroscopy (UBM) examinations revealed a rupture of Descemet membrane and intrastromal clefts in all eyes. In 11 of 13 eyes, the intrastromal clefts were connected to the anterior chamber.
Formation of intrastromal clefts may be an important factor in the development of acute hydrops in keratoconic eyes. The clefts may cause severe corneal edema and delay the closure of Descemet membrane during the resolution of corneal edema.
探讨圆锥角膜患者发生急性角膜水肿的可能相关因素。
前瞻性干预性病例系列研究。
对13例患有急性角膜水肿的圆锥角膜患者的13只患眼进行连续超声生物显微镜（UBM）检查。
超声生物显微镜（UBM）检查显示所有患眼的后弹力层破裂和基质内裂隙。13只眼中有11只，基质内裂隙与前房相连。
基质内裂隙的形成可能是圆锥角膜患眼发生急性角膜水肿的一个重要因素。这些裂隙可能导致严重的角膜水肿，并在角膜水肿消退过程中延迟后弹力层的闭合。
