Zelefsky Joseph R, Fine Howard F, Rubinstein Valeria J, Hsu Irene S, Finger Paul T
Manhattan Eye Ear and Throat Hospital, New York, NY 10016, USA.
Am J Ophthalmol. 2006 Jun;141(6):1144-7. doi: 10.1016/j.ajo.2006.01.033.
To report the onset of bilateral angle closure glaucoma resulting from ciliochoroidal effusions noted after taking escitalopram.
Case report.
A 41-year-old woman with a medical history of depression was placed on escitalopram and presented with acute bilateral angle closure glaucoma. A medical history and ophthalmic examination (including slit-lamp photography and high-frequency ultrasonography) were performed at the time of diagnosis and at resolution of her symptoms.
High-frequency ultrasonography revealed bilateral choroidal effusions with ciliary body detachments and angle closure. Attempts to reduce intraocular pressure with topical ocular antihypertensive drugs and subsequent laser peripheral iridotomy were unsuccessful. Over the course of four days, the use of topical cycloplegics, corticosteroids, and discontinuation of escitalopram resulted in normalization of intraocular pressures, deepening of anterior chamber depths, and resolution of her uveal effusions.
The use of escitalopram resulted in uveal effusions, angle rotation, and acute bilateral angle closure glaucoma. Discontinuation of escitalopram and corticosteroid therapy resulted in normalization of the patient's eyes.
报告服用艾司西酞普兰后出现睫状体脉络膜积液导致双侧闭角型青光眼的病例。
病例报告。
一名有抑郁症病史的41岁女性服用艾司西酞普兰后出现急性双侧闭角型青光眼。在诊断时和症状缓解时进行了病史采集和眼科检查（包括裂隙灯照相和高频超声检查）。
高频超声检查显示双侧脉络膜积液伴睫状体脱离和房角关闭。使用局部抗青光眼药物降低眼压以及随后进行激光周边虹膜切开术均未成功。在四天的时间里，使用局部睫状肌麻痹剂、皮质类固醇并停用艾司西酞普兰，使眼压恢复正常，前房深度加深，葡萄膜积液消退。
使用艾司西酞普兰导致葡萄膜积液、房角旋转和急性双侧闭角型青光眼。停用艾司西酞普兰和皮质类固醇治疗后，患者眼部恢复正常。
