Fundação Leiria de Andrade, Fortaleza, CE, Brazil.
Centro Universitário Christus, Fortaleza, CE, Brazil.
Arq Bras Oftalmol. 2021 Mar-Apr;84(2):170-173. doi: 10.5935/0004-2749.20210017.
Benzodiazepines are psychoactive drugs that are prescribed worldwide with limited information on their ocular side effects. Acute angle closure glaucoma is an adverse event with a high risk of blinding, especially in the elderly. We report two patients under 45 years old who presented with bilateral acute angle closure secondary to use of two long half-life benzodiazepines (clonazepam and alprazolam). In addition to suspending the use of these medications and administering ocular hypotensive drugs, both patients were successfully treated with bilateral peripheral laser iridotomy. To the best of our knowledge, this is the first report of bilateral acute angle closure secondary to the use of clonazepam and alprazolam.
苯二氮䓬类药物是具有精神活性的药物，在全球范围内被处方使用，但关于它们的眼部副作用的信息有限。急性闭角型青光眼是一种具有高致盲风险的不良事件，尤其是在老年人中。我们报告了两名 45 岁以下的患者，他们因使用两种半衰期长的苯二氮䓬类药物（氯硝西泮和阿普唑仑）而出现双侧急性闭角型青光眼。除了停用这些药物和给予眼部降压药物外，两名患者均成功接受了双侧周边激光虹膜切开术治疗。据我们所知，这是首例因使用氯硝西泮和阿普唑仑而导致双侧急性闭角型青光眼的报告。
