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准分子激光上皮下角膜磨镶术后角膜敏感性的恢复

Recovery of corneal sensitivity after laser-assisted subepithelial keratectomy.

作者信息

Wu Ying, Chu Ren Y, Zhou Xing T, Dai Jin H, Qu Xiao M, Rao Srinivas, Lam Dennis

机构信息

Eye and ENT Hospital, Fudan University, Shanghai, China.

出版信息

J Cataract Refract Surg. 2006 May;32(5):785-8. doi: 10.1016/j.jcrs.2006.01.066.

DOI:10.1016/j.jcrs.2006.01.066
PMID:16765795
Abstract

PURPOSE

To evaluate the recovery of corneal sensitivity after laser-assisted subepithelial keratectomy (LASEK) for myopia.

SETTING

Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.

METHODS

In this prospective interventional case series, central corneal sensitivity (CCS) was measured using a Cochet-Bonnet esthesiometer (Luneau Ophthalmologie) in 85 eyes of 50 patients before and 2 weeks, 1 month, 3 months, and 6 months after LASEK for the treatment of myopia. For analysis, the eyes were divided into 2 groups-the low-moderate myopia group (spherical equivalent [SE] -1.0 to -6.0 diopters [D]) and the high myopia group (SE -6.0 to -16.0 D)-and the correlation between ablation depth and CCS was evaluated.

RESULTS

In both groups, a significant decrease in CCS was present at 2 weeks and 1 month. In the low-moderate myopia group, the CCS recovered to preoperative values at 3 months. In the high myopia group, recovery of CCS was slower and preoperative values were reached only at the 6-month follow-up. Measured CCS was significantly correlated with the ablation depth used at the 3-month and 6-month examinations (r = -0.262 and r = -0.264, respectively; P<.05).

CONCLUSION

Recovery of corneal sensitivity began 1 month after LASEK and was completed by 3 months in eyes treated for low-moderate myopia and at 6 months in eyes with high myopia. The depth of ablation during surgery affected the recovery of corneal sensitivity.

摘要

目的

评估准分子激光上皮下角膜磨镶术(LASEK)治疗近视后角膜敏感性的恢复情况。

设置

中国上海复旦大学附属眼耳鼻喉科医院眼科。

方法

在这个前瞻性干预性病例系列研究中,使用科谢-博内眼压计(Luneau Ophthalmologie)对50例患者的85只眼睛在LASEK治疗近视前以及术后2周、1个月、3个月和6个月测量中央角膜敏感性(CCS)。为了进行分析,将眼睛分为两组——低度至中度近视组(等效球镜度[SE] -1.0至-6.0屈光度[D])和高度近视组(SE -6.0至-16.0 D)——并评估消融深度与CCS之间的相关性。

结果

在两组中,2周和1个月时CCS均显著降低。在低度至中度近视组中,CCS在3个月时恢复到术前值。在高度近视组中,CCS恢复较慢,仅在6个月随访时达到术前值。在3个月和6个月检查时测得的CCS与所使用的消融深度显著相关(分别为r = -0.262和r = -0.264;P<.05)。

结论

LASEK术后1个月开始恢复角膜敏感性,低度至中度近视患者的眼睛在3个月时恢复完成,高度近视患者的眼睛在6个月时恢复完成。手术中的消融深度影响角膜敏感性的恢复。

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