Wu Ying, Chu Ren Y, Zhou Xing T, Dai Jin H, Qu Xiao M, Rao Srinivas, Lam Dennis
Eye and ENT Hospital, Fudan University, Shanghai, China.
J Cataract Refract Surg. 2006 May;32(5):785-8. doi: 10.1016/j.jcrs.2006.01.066.
To evaluate the recovery of corneal sensitivity after laser-assisted subepithelial keratectomy (LASEK) for myopia.
Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China.
In this prospective interventional case series, central corneal sensitivity (CCS) was measured using a Cochet-Bonnet esthesiometer (Luneau Ophthalmologie) in 85 eyes of 50 patients before and 2 weeks, 1 month, 3 months, and 6 months after LASEK for the treatment of myopia. For analysis, the eyes were divided into 2 groups-the low-moderate myopia group (spherical equivalent [SE] -1.0 to -6.0 diopters [D]) and the high myopia group (SE -6.0 to -16.0 D)-and the correlation between ablation depth and CCS was evaluated.
In both groups, a significant decrease in CCS was present at 2 weeks and 1 month. In the low-moderate myopia group, the CCS recovered to preoperative values at 3 months. In the high myopia group, recovery of CCS was slower and preoperative values were reached only at the 6-month follow-up. Measured CCS was significantly correlated with the ablation depth used at the 3-month and 6-month examinations (r = -0.262 and r = -0.264, respectively; P<.05).
Recovery of corneal sensitivity began 1 month after LASEK and was completed by 3 months in eyes treated for low-moderate myopia and at 6 months in eyes with high myopia. The depth of ablation during surgery affected the recovery of corneal sensitivity.
评估准分子激光上皮下角膜磨镶术(LASEK)治疗近视后角膜敏感性的恢复情况。
中国上海复旦大学附属眼耳鼻喉科医院眼科。
在这个前瞻性干预性病例系列研究中,使用科谢-博内眼压计(Luneau Ophthalmologie)对50例患者的85只眼睛在LASEK治疗近视前以及术后2周、1个月、3个月和6个月测量中央角膜敏感性(CCS)。为了进行分析,将眼睛分为两组——低度至中度近视组(等效球镜度[SE] -1.0至-6.0屈光度[D])和高度近视组(SE -6.0至-16.0 D)——并评估消融深度与CCS之间的相关性。
在两组中,2周和1个月时CCS均显著降低。在低度至中度近视组中,CCS在3个月时恢复到术前值。在高度近视组中,CCS恢复较慢,仅在6个月随访时达到术前值。在3个月和6个月检查时测得的CCS与所使用的消融深度显著相关(分别为r = -0.262和r = -0.264;P<.05)。
LASEK术后1个月开始恢复角膜敏感性,低度至中度近视患者的眼睛在3个月时恢复完成,高度近视患者的眼睛在6个月时恢复完成。手术中的消融深度影响角膜敏感性的恢复。